Division of Viral and Rickettsial Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, U.S. Department of Health and Human Services, Atlanta, GA 30333, USA.
Pediatr Infect Dis J. 2010 Jun;29(6):483-8. doi: 10.1097/INF.0b013e3181cf8705.
The present study describes the rate and trends of childhood hospitalizations with Kawasaki syndrome (KS) in the United States.
Retrospective analysis of hospitalizations with KS among children <18 years of age in the United States using the Kids' Inpatient Database (1997, 2000, 2003, and 2006) and the Nationwide Inpatient Sample (1998-2007).
The KS-associated hospitalization rate for children <5 years of age was 20.8 (95% CI: 18.5-23.1) per 100,000 children in 2006. Annual rates remained constant during the study period, except for a peak in 2005. In 2006, 76.8% (SE = 0.9%) of an estimated 5523 (SE = 289) KS-associated hospitalizations among children <18 years of age were <5 years of age. The mean age for all children at hospitalization was 3.0 years (SE <0.1); 25.7 months (SE = 0.3) for children <5 years of age, and 24.8 months (SE = 0.4) and 27.1 months (SE = 0.5) for boys and girls, respectively. The rate for boys was higher than that for girls (24.2 [95% CI: 21.3-27.1] and 16.8 [95% CI: 14.7-18.9], respectively). The rate for Asian/Pacific Islander children (30.3 [95% CI: 20.2-40.4]) was the highest among the racial groups.
The national KS-associated annual hospitalization rate for children <5 years of age from 1997 to 2007 was relatively stable and was similar to previously published rates, except for an increase in 2005. Most hospitalizations were in children <3 years of age with few hospitalizations during the first 2 months of age. Children of Asian/Pacific Islander descent had the highest hospitalization rate.
本研究描述了美国儿童川崎病（KS）住院率及趋势。
采用美国儿童住院数据库（1997 年、2000 年、2003 年和 2006 年）和全国住院患者样本（1998-2007 年）对年龄<18 岁的儿童进行回顾性分析，观察 KS 相关住院情况。
2006 年，<5 岁儿童 KS 相关住院率为 20.8（95%CI：18.5-23.1）/10 万儿童。研究期间，除 2005 年略有升高外，年住院率基本保持不变。2006 年，估计年龄<18 岁的<5 岁儿童 5523 例（SE = 289）KS 相关住院患者中，76.8%（SE = 0.9%）为<5 岁。所有患儿住院时平均年龄为 3.0 岁（SE<0.1），<5 岁患儿为 25.7 个月（SE = 0.3），男孩和女孩分别为 24.8 个月（SE = 0.4）和 27.1 个月（SE = 0.5）。男孩的住院率高于女孩（分别为 24.2[95%CI：21.3-27.1]和 16.8[95%CI：14.7-18.9]）。亚洲/太平洋岛民儿童的住院率（30.3[95%CI：20.2-40.4]）在各种族中最高。
1997 年至 2007 年，<5 岁儿童川崎病的全国年住院率相对稳定，与以往报道的发病率相似，仅 2005 年略有升高。大多数住院患儿年龄<3 岁，<2 月龄的患儿住院较少。亚洲/太平洋岛民儿童的住院率最高。
