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摩洛哥与新冠病毒感染相关的儿童多系统炎症综合征(MIS-C)

Multisystem Inflammatory Syndrome in Children (MIS-C) Associated With COVID-19 Infection in Morocco.

作者信息

Amenzoui Naima, Zouiter Siham, Nassid Meriem, Kholaiq Halima, Belkhou Ikbal, Benhsaien Ibtihal, Ailal Fatima, Adnane Fatima, Jouhadi Zineb, Bousfiha Ahmed Aziz

机构信息

Clinical Immunology and Infectious Pediatrics Department, Abderrahim Harouchi Mother and Childrens Hospital, Casablanca, Morocco.

Laboratory of Clinical Immunology, Inflammation and Allergy (LICIA), Hassan II University of Casablanca Faculty of Medicine and Pharmacy, Morocco.

出版信息

Glob Pediatr Health. 2024 Oct 28;11:2333794X241286772. doi: 10.1177/2333794X241286772. eCollection 2024.

Abstract

. This study aims to describe the clinical and paraclinical characteristics of Multisysteminflammatory syndrome in children (MIS-C). . A retrospective study encompassing 52 children diagnosed with MIS-C according to the World Health Organization criteria, over a 3-year period at Abderrahim Harrouchi Hospital in Morocco. . The median age was 6 years (IQR: 1-14), with a sex ratio of 1.16 (28 boys and 24 girls). Clinical manifestations were predominantly characterized by fever in all cases (100%), respiratory and gastrointestinal symptoms in 30 cases (58%) and 23 cases (44%) respectively, and shock in 9 cases (17%). We noted a myocarditis in 6 cases (12%). The treatment comprised intravenous human Immunoglobulin combined with methylprednisolone in all patients (100%). . The characteristics of our MIS-C patients were similar to those in the literature, but more studies are needed to confirm these results.

摘要

本研究旨在描述儿童多系统炎症综合征(MIS-C)的临床和辅助检查特征。这是一项回顾性研究,在摩洛哥阿卜杜勒拉希姆·哈鲁奇医院对52名根据世界卫生组织标准诊断为MIS-C的儿童进行了为期3年的研究。中位年龄为6岁(四分位间距:1 - 14岁),性别比为1.16(28名男孩和24名女孩)。临床表现主要特征为所有病例均有发热(100%),30例(58%)有呼吸道症状,23例(44%)有胃肠道症状,9例(17%)有休克。我们注意到6例(12%)有心肌炎。所有患者(100%)的治疗包括静脉注射人免疫球蛋白联合甲泼尼龙。我们的MIS-C患者特征与文献中的相似,但需要更多研究来证实这些结果。

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本文引用的文献

9
Multisystem Inflammatory Syndrome in Children (MIS-C).儿童多系统炎症综合征(MIS-C)。
Curr Allergy Asthma Rep. 2022 May;22(5):53-60. doi: 10.1007/s11882-022-01031-4. Epub 2022 Mar 22.

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