University of Mainz, Children's Hospital, Mainz, Germany.
Cardiol J. 2010;17(1):20-8.
The aim of our study was to facilitate perioperative calculation of potential risk factors on the outcome of corrective surgery for children with tetralogy of Fallot.
The medical records of 81 (44 female and 37 male) out of a total of 87 patients undergoing complete surgical repair of tetralogy of Fallot between 1988 and 2004 at the Children's Hospital of the Johannes Gutenberg University of Mainz were reviewed. PATIENTS were divided into four categories, depending on the severity of pulmonary stenosis and cyanosis, as well as on the type of pulmonary circulation.
Additional malformations did not affect mortality rates, but did directly affect the number of pleural effusions, time of epinephrine administration, duration of surgery, bypass, and ischemia, as well as length of hospitalization and intensive care unit treatment. In contrast to longer periods of extracorporeal circulation and ischemia during surgery, which are directly related not only to more complex anatomical situations but also to higher mortality and complication rates, the much-debated question of age at surgery had no influence either on the surgical approach itself or on the post-operative outcome.
Our patient categorization, and evaluation of potential pre-operative risk factors and intraoperative parameters, should prove useful for the future planning and execution of therapeutic procedures in institutions around the world.
我们的研究旨在为法洛四联症患儿的矫正手术结果的围手术期计算潜在风险因素提供便利。
回顾了 1988 年至 2004 年间在美因茨约翰内斯古腾堡大学儿童医院接受完全法洛四联症矫正手术的 87 例患者中的 81 例（44 名女性和 37 名男性）的病历。根据肺动脉狭窄和发绀的严重程度以及肺循环类型，将患者分为四类。
附加畸形不会影响死亡率，但会直接影响胸腔积液的数量、肾上腺素的使用时间、手术时间、体外循环和缺血时间，以及住院时间和重症监护治疗时间。与手术期间体外循环和缺血时间较长直接相关的不仅是更复杂的解剖情况，还有更高的死亡率和并发症发生率，而备受争议的手术年龄问题对手术方法本身或术后结果均无影响。
我们的患者分类，以及对潜在术前风险因素和术中参数的评估，应有助于全球各机构未来的治疗方案规划和执行。
