Weber K T, Brilla C G, Janicki J S
Department of Medicine, University of Missouri-Columbia School of Medicine.
Hosp Pract (Off Ed). 1991 Apr 15;26(4):73-80. doi: 10.1080/21548331.1991.11704159.
The hallmark of myocardial hypertrophy associated with congestive failure is interstitial fibrosis. How does the fibrosis develop, and what can be done about it? Hormonal and hemodynamic factors are examined. Experimental studies with ACE inhibitors or aldosterone receptor antagonists suggest that the fibrosis may be prevented or reversed.
与充血性心力衰竭相关的心肌肥大的标志是间质纤维化。纤维化是如何发展的,又能对此做些什么?本文对激素和血流动力学因素进行了研究。使用血管紧张素转换酶抑制剂或醛固酮受体拮抗剂的实验研究表明,纤维化可能会被预防或逆转。