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抑郁和地理状况作为预测冠状动脉旁路移植手术结果的因素。

Depression and geographic status as predictors for coronary artery bypass surgery outcomes.

机构信息

Department of Educational Psychology, University of Houston, Houston, TX 77030, USA.

出版信息

J Rural Health. 2010 Winter;26(1):36-43. doi: 10.1111/j.1748-0361.2009.00263.x.

DOI:10.1111/j.1748-0361.2009.00263.x
PMID:20105266
Abstract

PURPOSE

To examine the relationships between depression, geographic status, and clinical outcomes following a coronary artery bypass grafting (CABG) surgery.

METHODS

Using the 2004 Nationwide Inpatient Sample database, we identified 63,061 discharge records of patients who underwent a primary CABG surgery (urban 57,247 and rural 5,814). We analyzed 7 demographic variables, 19 preoperative medical and psychiatric variables, and 2 outcome variables (ie, in-hospital mortality and length of stay). Logistic regression and multivariable regression analyses were used to assess urban-rural status and depression as independent predictors of in-hospital mortality and length of stay.

FINDINGS

Rural patients were more likely to have a comorbid depression diagnosis compared to urban patients (urban = 19.4%, rural = 21.4%, P < .001). After adjusting for confounding factors, having a comorbid depression diagnosis (B= 1.10, P < .001) and residing in a rural area (B= .986, P < .05) were associated with an increased length of in-hospital stay following CABG surgery. Furthermore, having a depression diagnosis (OR = 1.63, 95% CI = 1.45-2.21) and residing in a rural area (OR = 1.43, 95% CI = .896-1.45) were associated with an increased likelihood of in-hospital mortality.

CONCLUSIONS

Rural patients were more likely than urban ones to have a depression diagnosis. Depression was a significant independent predictor of both in-hospital mortality and length of stay for patients receiving CABG surgery. Also, rural patients had increased lengths of in-hospital stay as well as in-hospital mortality rates compared to those who resided in urban areas.

摘要

目的

探讨冠状动脉旁路移植术(CABG)后抑郁、地理位置与临床结局的关系。

方法

利用 2004 年全国住院患者样本数据库,我们确定了 63061 例行 CABG 手术的患者出院记录(城市 57247 例,农村 5814 例)。我们分析了 7 项人口统计学变量、19 项术前医学和精神科变量以及 2 项结局变量(即住院内死亡率和住院时间)。采用逻辑回归和多变量回归分析,评估城乡地位和抑郁作为住院内死亡率和住院时间的独立预测因素。

发现

与城市患者相比,农村患者更有可能合并抑郁诊断(城市患者为 19.4%,农村患者为 21.4%,P<0.001)。在调整混杂因素后,合并抑郁诊断(B=1.10,P<0.001)和居住在农村地区(B=0.986,P<0.05)与 CABG 术后住院时间延长相关。此外,存在抑郁诊断(OR=1.63,95%CI=1.45-2.21)和居住在农村地区(OR=1.43,95%CI=0.896-1.45)与住院内死亡率增加相关。

结论

农村患者比城市患者更有可能患有抑郁。抑郁是 CABG 手术患者住院内死亡率和住院时间的显著独立预测因素。此外,与居住在城市地区的患者相比,农村患者的住院时间和住院内死亡率均有所增加。

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