Section of Pediatric Surgery, Department of Surgery, The University of Michigan Medical School and The CS Mott Children's Hospital, Ann Arbor, MI, USA.
J Pediatr Surg. 2010 Jan;45(1):177-84; discussion 184. doi: 10.1016/j.jpedsurg.2009.10.029.
The fistula first initiative has led to increased efforts to create arteriovenous fistulas (AVFs) as primary dialysis access. Two-stage basilic vein transposition (BVT) allows maturation of smaller veins, often a limiting factor in the pediatric population, before elevation and use. We sought to determine whether using 2-stage BVT improves maturation, use, and patency compared with other AVFs, including arteriovenous (AV) grafts.
Thirty-one patients underwent AV access creation between 1997 and 2008. Data were collected on types of access, maturation, complications, and patency.
Forty-two AV access procedures were performed: 15 (36%) 2-stage BVT, 13 (31%) 1-stage BVT, 6 (14%) radiocephalic, 3 (7%) brachiocephalic, 1 (2%) brachiobrachial, and 4 (10%) AV grafts. Follow-up averaged 20.4 +/- 3.2 months for 2-stage BVT and 47.9+/-4.1 months for other AVFs (P < .001). All 2-stage BVT matured compared with 52% (14/27) of other AVFs (P = .001). More 2-stage BVTs (87%) were used for dialysis than other AVFs (48%, P = .024). Fistula failure occurred in 7% 2-stage BVT compared with 59% other AVFs (P = .001). One-year patency rates were 91% for 2-stage BVT vs 47% for other AVFs (P = .003).
Rates of fistula maturation, use, and patency are higher for 2-stage BVT with lower rates of failure. Two-stage BVT shows great promise as the preferred approach to creation of AVF in pediatric patients, especially those with smaller veins.
fistula first 倡议促使人们加大力度创建动静脉瘘(AVF)作为主要透析通路。二期肱静脉转位术(BVT)可使较小的静脉成熟,这在儿科人群中常常是一个限制因素,然后再将其提升并使用。我们试图确定与其他动静脉(AV)移植物等其他 AVF 相比,使用两阶段 BVT 是否能改善成熟度、使用率和通畅率。
1997 年至 2008 年间,31 例患者接受了血管通路的建立。收集了通路类型、成熟度、并发症和通畅率的数据。
共进行了 42 次 AV 通路手术:15 例(36%)为两阶段 BVT,13 例(31%)为单阶段 BVT,6 例(14%)为桡动脉-头静脉,3 例(7%)为肱动脉-头静脉,1 例(2%)为肱动脉-肱静脉,4 例(10%)为 AV 移植物。两阶段 BVT 的平均随访时间为 20.4+/-3.2 个月,其他 AVF 为 47.9+/-4.1 个月(P<.001)。所有两阶段 BVT 均成熟,而其他 AVF 的成熟率为 52%(14/27)(P=.001)。与其他 AVF(48%,P=.024)相比,更多的两阶段 BVT(87%)用于透析。两阶段 BVT 的瘘管失败率为 7%,而其他 AVF 为 59%(P=.001)。两阶段 BVT 的 1 年通畅率为 91%,而其他 AVF 为 47%(P=.003)。
两阶段 BVT 的瘘成熟、使用和通畅率较高,失败率较低。两阶段 BVT 为儿科患者创建 AVF 提供了一种很有前途的方法,特别是对于那些静脉较小的患者。