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肱动脉-贵要静脉动静脉内瘘:不同手术技术及其对内瘘通畅性和透析相关并发症的影响

Brachiobasilic arteriovenous fistula: different surgical techniques and their effects on fistula patency and dialysis-related complications.

作者信息

Hossny Ahmed

机构信息

Vascular Surgery Department, Faculty of Medicine, Menofia University, Egypt.

出版信息

J Vasc Surg. 2003 Apr;37(4):821-6. doi: 10.1067/mva.2003.181.

Abstract

OBJECTIVE

Easy access to the vascular system is vital in patients with chronic renal failure undergoing long-term hemodialysis. Such patients often require multiple operations, and options for secondary or tertiary access procedures become increasingly limited. Brachiobasilic arteriovenous fistula offers excellent access in such difficult cases and is increasingly preferred over prosthetic grafts. Many surgical techniques have been described to create such fistulas. The purpose of this study was to determine the difference in long-term patency and dialysis-related complications among various techniques.

METHODS

Seventy brachiobasilic arteriovenous fistulas were constructed in 70 patients. This was the secondary or tertiary access in 88.6% of patients. The basilic vein was transposed in 30 patients and elevated in 40 patients; twenty veins were elevated with a one-stage technique, and 20 were elevated with a two-stage (delayed elevation) technique.

RESULTS

The early failure rate was 5.7% in the entire group. Sixty-six fistulas (94.3%) were successfully used for dialysis. Mean follow-up was 25.8 months (range, 4-36 months). Four fistulas (5.7%) required additional procedures during follow-up, 2 in the transposed vein group and 2 in the elevated vein group. Cumulative secondary patency rate, measured with the Kaplan-Meier survival method, was 86.7%, 90%, and 84.2% at 1 year for the transposed, one-stage, and two-stage elevation procedures, respectively, compared with 82.8%, 70%, and 68.4% at 2 years. The difference was statistically nonsignificant. Forty-two complications developed in 29 (43.9%) fistulas. Thirteen fistulas (19.7%) had more than one complication. Twelve complications in 10 fistulas (35.7%) were recorded in the transposition group, 15 complications in 9 fistulas (47.4%) in the one-stage elevation group, and 15 complications in 10 fistulas (52.6%) in the two-stage elevation group. The total complication rate was higher in the elevated fistulas (71.4% vs 28.6%); the difference was statistically highly significant (P <.001). The most common complication was arm edema (21.2%; n = 14), followed by puncture site-related hematoma (16.7%; n = 11) and thrombosis (16.7%; n = 11). Hematoma was statistically more common (P <.05) in the elevated vein group (26.3% vs 3.6%). The difference in thrombosis between the transposition and elevation groups (23.7% vs 7.1%) was not significant. Hematoma preceded thrombosis in 63.7% (7 of 11) of the fistulas, and it was the major predisposing factor for fistula failure. Transposed vein was easier to manage by dialysis staff. All nurses were satisfied with the transposed veins, but only 53.3% were satisfied with the elevated veins; the difference was statistically highly significant (P <.001).

CONCLUSION

Available techniques for creating brachiobasilic arteriovenous fistula are associated with good patency rate, and most related complications can be treated conservatively without loss of the fistula. Among the various procedures, transposition has a lower complication rate and is favored by the dialysis staff dealing with such fistulas.

摘要

目的

对于接受长期血液透析的慢性肾衰竭患者而言,易于建立血管通路至关重要。此类患者常常需要多次手术,而二级或三级血管通路手术的选择日益受限。肱动脉-贵要静脉内瘘在这类困难病例中能提供良好的血管通路,并且相较于人工血管移植物越来越受到青睐。已经描述了许多用于建立此类内瘘的手术技术。本研究的目的是确定不同技术在长期通畅率和透析相关并发症方面的差异。

方法

为70例患者建立了70个肱动脉-贵要静脉内瘘。这是88.6%患者的二级或三级血管通路。30例患者进行了贵要静脉转位,40例患者进行了贵要静脉抬高;20条静脉采用一期技术抬高,20条静脉采用二期(延迟抬高)技术抬高。

结果

整个组的早期失败率为5.7%。66个内瘘(94.3%)成功用于透析。平均随访时间为25.8个月(范围4 - 36个月)。4个内瘘(5.7%)在随访期间需要额外手术,转位静脉组2个,抬高静脉组2个。采用Kaplan-Meier生存法测量,转位、一期和二期抬高手术在1年时的累积二级通畅率分别为86.7%、90%和84.2%,2年时分别为82.8%、70%和68.4%。差异无统计学意义。29个(43.9%)内瘘出现了42种并发症。13个内瘘(19.7%)有不止一种并发症。转位组10个内瘘(35.7%)出现12种并发症,一期抬高组9个内瘘(47.4%)出现15种并发症,二期抬高组10个内瘘(52.6%)出现15种并发症。抬高内瘘的总并发症发生率更高(71.4%对28.6%);差异有高度统计学意义(P <.001)。最常见的并发症是手臂水肿(21.2%;n = 14),其次是穿刺部位相关血肿(16.7%;n = 11)和血栓形成(16.7%;n = 11)。血肿在抬高静脉组在统计学上更常见(P <.05)(26.3%对3.6%)。转位组和抬高组之间血栓形成的差异(23.7%对7.1%)不显著。63.7%(11个中的7个)的内瘘血肿先于血栓形成,且是内瘘失败的主要诱发因素。转位静脉更易于透析工作人员管理。所有护士对转位静脉都满意,但只有53.3%对抬高静脉满意;差异有高度统计学意义(P <.001)。

结论

现有的建立肱动脉-贵要静脉内瘘的技术具有良好的通畅率,并且大多数相关并发症可以保守治疗而不导致内瘘丧失。在各种手术中,转位的并发症发生率较低,并且受到处理此类内瘘的透析工作人员的青睐。

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