抗 N-甲基-D-天冬氨酸受体脑炎患儿 4 岁。

Anti-N-methyl-D-aspartate-receptor encephalitis in a four-year-old girl.

机构信息

Child Neurology and Psychiatry Unit, G. Gaslini Institute and University of Genova, Largo G. Gaslini 5, 16147 Genova, Italy.

出版信息

J Pediatr. 2010 Feb;156(2):332-4. doi: 10.1016/j.jpeds.2009.07.057.

DOI:10.1016/j.jpeds.2009.07.057

PMID:20105645

Abstract

Anti-N-methyl-D-aspartate-receptor encephalitis is a recently identified autoimmune disorder. We report on a 4-year-old girl presenting with seizures after nonspecific viral-like symptoms, progressing to severe aphasia, upper limb dyskinesias, fluctuation in consciousness, and inability to walk. Anti-N-methyl-D-aspartate-receptor encephalitis should be included in the differential diagnosis of acute/subacute encephalitis in children.

摘要

抗 N-甲基-D-天冬氨酸受体脑炎是一种新近确定的自身免疫性疾病。我们报告了一例 4 岁女孩，在出现非特异性类似病毒症状后出现癫痫发作，随后进展为严重的失语症、上肢运动障碍、意识波动和无法行走。抗 N-甲基-D-天冬氨酸受体脑炎应纳入儿童急性/亚急性脑炎的鉴别诊断。