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比较 2 型糖尿病中德谷胰岛素和甘精胰岛素:更多的相似之处而非差异。述评。

Comparing insulins detemir and glargine in type 2 diabetes: more similarities than differences. Commentary.

机构信息

Division of Endocrinology and Molecular Medicine, University of Kentucky, Lexington, KY 40506, USA.

出版信息

Postgrad Med. 2010 Jan;122(1):201-3. doi: 10.3810/pgm.2010.01.2116.

DOI:10.3810/pgm.2010.01.2116
PMID:20107306
Abstract

The efficacy of either detemir or glargine is comparable in subjects with type 2 diabetes when combined with insulin aspart in a basal-bolus regimen. Subjects randomized to detemir used slightly higher daily insulin doses, but gained less weight on average than glargine-treated subjects.

摘要

在基础-餐时胰岛素方案中,与门冬胰岛素联合应用时,地特胰岛素或甘精胰岛素的疗效在 2 型糖尿病患者中相当。与甘精胰岛素组相比,随机分配至地特胰岛素组的患者每日胰岛素用量略高,但平均体重增加较少。

相似文献

1
Comparing insulins detemir and glargine in type 2 diabetes: more similarities than differences. Commentary.比较 2 型糖尿病中德谷胰岛素和甘精胰岛素:更多的相似之处而非差异。述评。
Postgrad Med. 2010 Jan;122(1):201-3. doi: 10.3810/pgm.2010.01.2116.
2
A 52-week, multinational, open-label, parallel-group, noninferiority, treat-to-target trial comparing insulin detemir with insulin glargine in a basal-bolus regimen with mealtime insulin aspart in patients with type 2 diabetes.一项为期52周的多国、开放标签、平行组、非劣效性、达标治疗试验,在2型糖尿病患者中,比较德谷胰岛素与甘精胰岛素在基础-餐时胰岛素方案中联合门冬胰岛素的疗效。
Clin Ther. 2008 Nov;30(11):1976-87. doi: 10.1016/j.clinthera.2008.11.001.
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Comparison of insulin detemir and insulin glargine in a basal-bolus regimen, with insulin aspart as the mealtime insulin, in patients with type 1 diabetes: a 52-week, multinational, randomized, open-label, parallel-group, treat-to-target noninferiority trial.在基础-餐时胰岛素方案中,将门冬胰岛素作为餐时胰岛素,比较地特胰岛素和甘精胰岛素治疗 1 型糖尿病患者的 52 周、多国、随机、开放标签、平行组、治疗达标非劣效性试验。
Clin Ther. 2009 Oct;31(10):2086-97. doi: 10.1016/j.clinthera.2009.10.006.
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Newer agents for blood glucose control in type 2 diabetes: systematic review and economic evaluation.新型 2 型糖尿病血糖控制药物:系统评价和经济评估。
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A comparison of insulin use, glycemic control, and health care costs with insulin detemir and insulin glargine in insulin-naive patients with type 2 diabetes.在初治2型糖尿病患者中比较地特胰岛素和甘精胰岛素的胰岛素使用情况、血糖控制及医疗费用。
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Insulin detemir versus insulin glargine for type 2 diabetes mellitus.地特胰岛素与甘精胰岛素治疗2型糖尿病的比较。
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Re: trial comparing insulin detemir with insulin glargine.关于:比较地特胰岛素与甘精胰岛素的试验。
Clin Ther. 2009 May;31(5):1124-5; author reply 1125-6. doi: 10.1016/j.clinthera.2009.05.004.
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Once-daily insulin detemir is comparable to once-daily insulin glargine in providing glycaemic control over 24 h in patients with type 2 diabetes: a double-blind, randomized, crossover study.在2型糖尿病患者中,每日一次的地特胰岛素在24小时血糖控制方面与每日一次的甘精胰岛素相当:一项双盲、随机、交叉研究。
Diabetes Obes Metab. 2009 Jan;11(1):69-71. doi: 10.1111/j.1463-1326.2008.01014.x.
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Safety and efficacy of insulin detemir basal-bolus therapy in type 1 diabetes patients: 14-week data from the European cohort of the PREDICTIVE study.德谷胰岛素基础-餐时疗法在1型糖尿病患者中的安全性和有效性:来自PREDICTIVE研究欧洲队列的14周数据。
Curr Med Res Opin. 2008 Feb;24(2):369-76. doi: 10.1185/030079908x260835.
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Comparison of insulin detemir and insulin glargine using a basal-bolus regimen in a randomized, controlled clinical study in patients with type 2 diabetes.在一项针对2型糖尿病患者的随机对照临床研究中,使用基础-餐时方案比较地特胰岛素和甘精胰岛素。
Diabetes Metab Res Rev. 2009 Sep;25(6):542-8. doi: 10.1002/dmrr.989.

引用本文的文献

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A Retrospective Observational Study of Insulin Glargine in Type 2 Diabetic Patients with Advanced Chronic Kidney Disease.甘精胰岛素用于晚期慢性肾病2型糖尿病患者的回顾性观察研究
Cureus. 2019 Nov 18;11(11):e6191. doi: 10.7759/cureus.6191.
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Insulin Degludec, The New Generation Basal Insulin or Just another Basal Insulin?德谷胰岛素,新一代基础胰岛素还是只是另一种基础胰岛素?
Clin Med Insights Endocrinol Diabetes. 2012;5:31-7. doi: 10.4137/CMED.S9494. Epub 2012 Apr 11.
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An update on the treatment of type 1 and type 2 diabetes mellitus: focus on insulin detemir, a long-acting human insulin analog.
1型和2型糖尿病治疗的最新进展:聚焦于长效人胰岛素类似物地特胰岛素。
Vasc Health Risk Manag. 2010 Jun 1;6:399-410. doi: 10.2147/vhrm.s10397.