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[墨西哥献血者血液中抗体的检测]

[Detection of antibodies present in blood donors in Mexico].

作者信息

Serrano Machuca José J, Villarreal Ríos Enrique, Galicia Rodríguez Liliana, Vargas Daza Emma R, Martínez González Lidia, Mejía Damián Alberto F

机构信息

Banco de Sangre, Hospital General Regional No 1, Instituto Mexicano del Seguro Social, Querétaro, Qro., México.

出版信息

Rev Panam Salud Publica. 2009 Oct;26(4):355-9. doi: 10.1590/s1020-49892009001000011.

Abstract

OBJECTIVE

To detect antibodies to six potentially blood-borne infections in blood donors at a social security institute in Querétaro, Mexico.

METHODS

A cross-sectional, retrospective, descriptive study was performed using data from the blood bank records of the General Regional Hospital No. 1, Mexican Social Security Institute (IMSS). From the 6 929 registered donors, those with any antibody to brucellosis, Chagas' disease, hepatitis B, hepatitis C, syphilis, and HIV were identified. For the cases presenting any of these infections, the following demographics were analyzed: age, gender, marital status, education, home address, and number of donations made. To estimate overall prevalence, the number of donors with any of the antibodies was divided by the total donors, and then by each of the various infections.

RESULTS

Of the 6 929 donors, 144 were detected with some type of circulating antibody of the six potentially blood-borne infections, with a total prevalence of 2.07% (0-4.4). The prevalence of blood donors with antibodies for hepatitis C was 0.721% (95%CI: 0.522-0.920) and Chagas' disease, 0.649% (95%CI: 0.460-0.838).

CONCLUSIONS

Identifying the prevalence of blood donors with antibodies for any of these six, potentially blood-borne infections, allows the blood bank at the General Regional Hospital No. 1 to establish its own epidemiologic profiling. Chagas' disease proved to be emergent, calling for urgent control efforts.

摘要

目的

检测墨西哥克雷塔罗州一家社会保障机构献血者中六种潜在血源性感染的抗体。

方法

采用墨西哥社会保障局第一综合区域医院血库记录的数据进行横断面、回顾性、描述性研究。在6929名登记献血者中,识别出患有布鲁氏菌病、恰加斯病、乙型肝炎、丙型肝炎、梅毒和艾滋病毒任何一种抗体的献血者。对于出现这些感染的病例,分析以下人口统计学特征:年龄、性别、婚姻状况、教育程度、家庭住址和献血次数。为了估计总体患病率,将患有任何一种抗体的献血者人数除以献血者总数,然后再除以各种感染类型的人数。

结果

在6929名献血者中,有144人被检测出患有六种潜在血源性感染中的某种循环抗体,总患病率为2.07%(0 - 4.4)。丙型肝炎抗体献血者的患病率为0.721%(95%置信区间:0.522 - 0.920),恰加斯病抗体献血者的患病率为0.649%(95%置信区间:0.460 - 0.838)。

结论

确定这六种潜在血源性感染中任何一种抗体的献血者患病率,有助于第一综合区域医院血库建立自己的流行病学概况。恰加斯病已成为突出问题,需要紧急采取防控措施。

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