Holdt M, Jurklies C, Schueler A, Otterbach F, Bornfeld N
Zentrum für Augenheilkunde, Universitätsklinikum Essen.
Klin Monbl Augenheilkd. 2009 Dec;226(12):1017-22. doi: 10.1055/s-0028-1109944. Epub 2009 Dec 15.
Intraocular medulloepithelioma is an extremely rare unilateral intraocular tumor arising from the nonpigmented ciliary epithelium. Medulloepitheliomas may be classified as benign and malignant and as teratoid and nonteratoid tumors. As a rule a long latency period occurs after first symptoms until the final diagnosis of a medulloepithelioma is made. Differential diagnosis includes in particular unilateral retinoblastoma. Intraocular medulloepithelioma may occur as masquerade-syndrome simulating uveitis. We present 10 patients with intraocular medulloepithelioma. In 7 of these patients the eye had to be enucleated. Metastasis did not occur, but epiretinal tumor seeding did occur in one patient. In one of the 3 not enucleated eyes, ruthenium-106 brachytherapy could salvage the tumor containing eye.
眼内髓上皮瘤是一种极其罕见的单侧眼内肿瘤，起源于无色素睫状体上皮。髓上皮瘤可分为良性和恶性，以及畸胎样和非畸胎样肿瘤。通常，从首次出现症状到最终诊断为髓上皮瘤会有很长的潜伏期。鉴别诊断尤其包括单侧视网膜母细胞瘤。眼内髓上皮瘤可能表现为伪装综合征，模拟葡萄膜炎。我们报告了10例眼内髓上皮瘤患者。其中7例患者的眼睛不得不被摘除。未发生转移，但有1例患者发生了视网膜下肿瘤播散。在3只未摘除眼球的患者中，有1只眼通过钌-106近距离放疗挽救了含有肿瘤的眼睛。
