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金鱼体内的达尼列夫斯基锥虫:康复金鱼的保护性免疫本质

Trypanosoma danilewskyi in Carassius auratus: the nature of protective immunity in recovered goldfish.

作者信息

Islam A K, Woo P T

机构信息

Department of Zoology, University of Guelph, Ontario, Canada.

出版信息

J Parasitol. 1991 Apr;77(2):258-62.

PMID:2010858
Abstract

Trypanosoma danilewskyi is pathogenic to goldfish, Carassius auratus; the number that survived an infection was related to the size of inoculum, i.e., the mortality was low when the inoculum was small. Most fish that had prior exposure(s) to the parasite survived subsequent homologous challenge(s) and were protected for at least 89 days. The immunity was nonsterile as low numbers of parasites were detected in the blood of some recovered fish. Intraperitoneal injection of corticosteroid in recovered fish significantly increased the number of trypanosomes in peripheral blood of some fish. Although most recovered fish were protected from challenge, a few died from high parasitemia after challenge.

摘要

达尼列夫斯基锥虫对金鱼(Carassius auratus)具有致病性;感染后存活的数量与接种量大小有关,即接种量小时死亡率较低。大多数先前接触过该寄生虫的鱼在随后的同源攻击中存活下来,并受到至少89天的保护。这种免疫是非无菌的,因为在一些康复鱼的血液中检测到少量寄生虫。对康复鱼进行腹腔注射皮质类固醇会显著增加一些鱼外周血中的锥虫数量。尽管大多数康复鱼受到保护免受攻击,但仍有少数在攻击后因高寄生虫血症而死亡。

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Trypanosoma danilewskyi in Carassius auratus: the nature of protective immunity in recovered goldfish.金鱼体内的达尼列夫斯基锥虫:康复金鱼的保护性免疫本质
J Parasitol. 1991 Apr;77(2):258-62.
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