Barabash R, Moreno-Suárez F G, Rodríguez L, Molina A M, Conejo-Mir J
Servicio de Dermatología, Hospitales Universitarios Virgen del Rocío, Sevilla.
Actas Dermosifiliogr. 2010 Jan-Feb;101(1):76-80.
Nelson syndrome is a rare cause of generalized mucocutaneous hyperpigmentation. Its clinical manifestations are due to excessive secretion of adrenocorticotropic hormone from a pituitary adenoma, which develops after bilateral therapeutic adrenalectomy. As this operation has fallen into disuse, Nelson syndrome is now extremely rare and difficult to recognize. We present a very severe case of generalized hyperpigmentation due to Nelson syndrome in a 37-year-old woman.
尼尔森综合征是导致全身性黏膜皮肤色素沉着的罕见原因。其临床表现是由于垂体腺瘤分泌过多促肾上腺皮质激素所致，该腺瘤在双侧治疗性肾上腺切除术后发生。由于这种手术已不再使用，尼尔森综合征现在极为罕见且难以识别。我们报告了一名37岁女性因尼尔森综合征导致全身性色素沉着的严重病例。
