Department of Neuroradiology, Charité Centrum 6, Campus Mitte, Charité-University Medicine Berlin, Germany.
AJNR Am J Neuroradiol. 2010 Jun;31(6):1003-9. doi: 10.3174/ajnr.A1971. Epub 2010 Jan 28.
Recently introduced 320-detector row CT enables whole brain perfusion imaging compared to a limited scanning area in 64-detector row CT. Our aim was to evaluate patient radiation exposure in comprehensive stroke imaging by using multidetector row CT consisting of standard CT of the head, CTA of cerebral and cervical vessels, and CTP.
Organ doses were measured by using LiF-TLDs located at several organ sites in an Alderson-Rando phantom. Effective doses were derived from these measurements. Stroke protocols including noncontrast head CT, CTA of cerebral and cervical vessels, and CTP were performed on 320- and 64-detector row scanners.
Measured effective doses for the different scanning protocols ranged between 1.61 and 4.56 mSv, resulting in an effective dose for complete stroke imaging of 7.52/7.54 mSv (m/f) for 64-detector row CT and 10.56/10.6 mSv (m/f) for 320-detector row CT. The highest organ doses within the area of the primary beam were measured in the skin (92 mGy) and cerebral hemispheres (69.91 mGy). Use of an eye-protection device resulted in a 54% decrease of the lens dose measured for the combo protocol for whole-brain perfusion with the 320-detector row CT scanner.
Phantom measurements indicate that comprehensive stroke imaging with multidetector row CT may result in effective radiation doses from 7.52 mSv (64-detector row CT) to 10.6 mSv (320-detector row CT). The technique of 320-detector row CT offers additional information on the time course of vascular enhancement and whole-brain perfusion. Physicians should weigh the potential of the new technique against the higher radiation dose that is needed. Critical doses that would cause organ damage were not reached.
最近推出的 320 排 CT 扫描仪可实现全脑灌注成像,而 64 排 CT 扫描仪仅能实现有限扫描区域的成像。本研究旨在评估使用包括头部标准 CT、脑颈血管 CTA 和 CTP 的多排 CT 进行全面脑卒中成像时患者的辐射暴露。
使用 LiF-TLD 在 Alderson-Rando 体模中的几个器官部位测量器官剂量。从这些测量中得出有效剂量。对 320 排和 64 排扫描仪进行了包括非对比头部 CT、脑颈血管 CTA 和 CTP 的脑卒中协议扫描。
不同扫描方案的测量有效剂量范围为 1.61 至 4.56 mSv,因此 64 排 CT 的完整脑卒中成像有效剂量为 7.52/7.54 mSv(男/女),320 排 CT 的有效剂量为 10.56/10.6 mSv(男/女)。初级线束区域内最高的器官剂量测量值出现在皮肤(92 mGy)和大脑半球(69.91 mGy)。使用眼部保护装置可使 320 排 CT 全脑灌注组合方案测量的晶状体剂量降低 54%。
体模测量表明,多排 CT 进行全面脑卒中成像可能导致有效剂量为 7.52 mSv(64 排 CT)至 10.6 mSv(320 排 CT)。320 排 CT 技术可提供关于血管增强和全脑灌注时间过程的额外信息。医生应权衡新技术的潜在获益与所需的更高辐射剂量。尚未达到可能导致器官损伤的临界剂量。