Suppr超能文献

多排探测器 CT 对全面性脑卒中成像患者的剂量暴露:320 排与 64 排 CT 扫描仪的比较。

Dose exposure of patients undergoing comprehensive stroke imaging by multidetector-row CT: comparison of 320-detector row and 64-detector row CT scanners.

机构信息

Department of Neuroradiology, Charité Centrum 6, Campus Mitte, Charité-University Medicine Berlin, Germany.

出版信息

AJNR Am J Neuroradiol. 2010 Jun;31(6):1003-9. doi: 10.3174/ajnr.A1971. Epub 2010 Jan 28.

Abstract

BACKGROUND AND PURPOSE

Recently introduced 320-detector row CT enables whole brain perfusion imaging compared to a limited scanning area in 64-detector row CT. Our aim was to evaluate patient radiation exposure in comprehensive stroke imaging by using multidetector row CT consisting of standard CT of the head, CTA of cerebral and cervical vessels, and CTP.

MATERIAL AND METHODS

Organ doses were measured by using LiF-TLDs located at several organ sites in an Alderson-Rando phantom. Effective doses were derived from these measurements. Stroke protocols including noncontrast head CT, CTA of cerebral and cervical vessels, and CTP were performed on 320- and 64-detector row scanners.

RESULTS

Measured effective doses for the different scanning protocols ranged between 1.61 and 4.56 mSv, resulting in an effective dose for complete stroke imaging of 7.52/7.54 mSv (m/f) for 64-detector row CT and 10.56/10.6 mSv (m/f) for 320-detector row CT. The highest organ doses within the area of the primary beam were measured in the skin (92 mGy) and cerebral hemispheres (69.91 mGy). Use of an eye-protection device resulted in a 54% decrease of the lens dose measured for the combo protocol for whole-brain perfusion with the 320-detector row CT scanner.

CONCLUSIONS

Phantom measurements indicate that comprehensive stroke imaging with multidetector row CT may result in effective radiation doses from 7.52 mSv (64-detector row CT) to 10.6 mSv (320-detector row CT). The technique of 320-detector row CT offers additional information on the time course of vascular enhancement and whole-brain perfusion. Physicians should weigh the potential of the new technique against the higher radiation dose that is needed. Critical doses that would cause organ damage were not reached.

摘要

背景与目的

最近推出的 320 排 CT 扫描仪可实现全脑灌注成像,而 64 排 CT 扫描仪仅能实现有限扫描区域的成像。本研究旨在评估使用包括头部标准 CT、脑颈血管 CTA 和 CTP 的多排 CT 进行全面脑卒中成像时患者的辐射暴露。

材料与方法

使用 LiF-TLD 在 Alderson-Rando 体模中的几个器官部位测量器官剂量。从这些测量中得出有效剂量。对 320 排和 64 排扫描仪进行了包括非对比头部 CT、脑颈血管 CTA 和 CTP 的脑卒中协议扫描。

结果

不同扫描方案的测量有效剂量范围为 1.61 至 4.56 mSv,因此 64 排 CT 的完整脑卒中成像有效剂量为 7.52/7.54 mSv(男/女),320 排 CT 的有效剂量为 10.56/10.6 mSv(男/女)。初级线束区域内最高的器官剂量测量值出现在皮肤(92 mGy)和大脑半球(69.91 mGy)。使用眼部保护装置可使 320 排 CT 全脑灌注组合方案测量的晶状体剂量降低 54%。

结论

体模测量表明,多排 CT 进行全面脑卒中成像可能导致有效剂量为 7.52 mSv(64 排 CT)至 10.6 mSv(320 排 CT)。320 排 CT 技术可提供关于血管增强和全脑灌注时间过程的额外信息。医生应权衡新技术的潜在获益与所需的更高辐射剂量。尚未达到可能导致器官损伤的临界剂量。

相似文献

3
Effective dose to patient measurements for flat-detector computed tomography protocols in acute stroke care.
Eur Radiol. 2020 Sep;30(9):5082-5088. doi: 10.1007/s00330-020-06891-w. Epub 2020 Apr 28.
7
Radiation exposure in perfusion CT of the brain.
J Comput Assist Tomogr. 2014 Jan-Feb;38(1):25-8. doi: 10.1097/RCT.0b013e3182a3f9a0.
8
Recent Update on Radiation Dose Assessment for the State-of-the-Art Coronary Computed Tomography Angiography Protocols.
PLoS One. 2016 Aug 23;11(8):e0161543. doi: 10.1371/journal.pone.0161543. eCollection 2016.
9

引用本文的文献

1
Portable head CT motion artifact correction via diffusion-based generative model.
Comput Med Imaging Graph. 2025 Jan;119:102478. doi: 10.1016/j.compmedimag.2024.102478. Epub 2024 Dec 13.
2
Clinical Applications of Conebeam CTP Imaging in Cerebral Disease: A Systematic Review.
AJNR Am J Neuroradiol. 2023 Aug;44(8):922-927. doi: 10.3174/ajnr.A7930. Epub 2023 Jul 6.
4
A dynamic simulation framework for CT perfusion in stroke assessment built from first principles.
Med Phys. 2021 Jul;48(7):3500-3510. doi: 10.1002/mp.14887. Epub 2021 May 9.
6
CT-perfusion in peripheral arterial disease - Correlation with angiographic and hemodynamic parameters.
PLoS One. 2019 Sep 27;14(9):e0223066. doi: 10.1371/journal.pone.0223066. eCollection 2019.
8
A "one-stop-shop" 4D CTA protocol using 320-row CT for advanced imaging in acute ischemic stroke: a technical note.
Eur Radiol. 2019 Sep;29(9):4930-4936. doi: 10.1007/s00330-019-06041-x. Epub 2019 Feb 15.
9
Comparative accuracy of CT perfusion in diagnosing acute ischemic stroke: A systematic review of 27 trials.
PLoS One. 2017 May 17;12(5):e0176622. doi: 10.1371/journal.pone.0176622. eCollection 2017.

本文引用的文献

1
Computed tomography dose assessment for a 160 mm wide, 320 detector row, cone beam CT scanner.
Phys Med Biol. 2009 May 21;54(10):3141-59. doi: 10.1088/0031-9155/54/10/012. Epub 2009 May 6.
3
320-slice CT neuroimaging: initial clinical experience and image quality evaluation.
Br J Radiol. 2009 Jul;82(979):561-70. doi: 10.1259/bjr/27721218. Epub 2009 Feb 16.
5
Concepts for dose determination in flat-detector CT.
Phys Med Biol. 2008 Jul 7;53(13):3551-66. doi: 10.1088/0031-9155/53/13/011. Epub 2008 Jun 13.
7
The trouble with CTD100.
Med Phys. 2007 Apr;34(4):1364-71. doi: 10.1118/1.2713240.
9
Conversion factor for CT dosimetry to assess patient dose using a 256-slice CT scanner.
Br J Radiol. 2006 Nov;79(947):888-92. doi: 10.1259/bjr/66519303. Epub 2006 May 25.
10
Comparison of patient doses in 256-slice CT and 16-slice CT scanners.
Br J Radiol. 2006 Jan;79(937):56-61. doi: 10.1259/bjr/39775216.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验