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阿尔茨海默病患者日常生活基本活动丧失模式:法国 REAL 队列的横断面研究。

Patterns of loss of basic activities of daily living in Alzheimer patients: A cross-sectional study of the French REAL cohort.

机构信息

Service de Médecine Gériatrique, AP-HP, Hôpital Sainte-Périne, Paris, France.

出版信息

Dement Geriatr Cogn Disord. 2010;29(1):46-54. doi: 10.1159/000264632. Epub 2010 Jan 27.

Abstract

BACKGROUND/AIMS: To characterize loss of basic activities of daily living (BADL) in 687 Alzheimer's disease (AD) community-dwelling patients included in the French REAL cohort.

METHODS

Patients had mild to moderately severe AD, and the mean age was 77.8 years. Patterns of loss of the 6 BADL were described at inclusion using the Lawton scale.

RESULTS

With 6 binary BADL scores, each patient presented at inclusion a set of losses. For 53% of women, the sets of losses were included within each other or were identical, adding losses in physical ambulation, grooming, bathing, dressing, toilet and feeding, respectively. For 47% of men, a similar sequence was identified, with loss of dressing occurring secondly. A global cohesion of sets of losses was found for 87% of women and 86% of men. The Lawton scale is very useful for the assessment of AD patients.

摘要

背景/目的:对纳入法国 REAL 队列的 687 例阿尔茨海默病(AD)社区居住患者丧失基本日常生活活动(BADL)的特征进行描述。

方法

患者有轻至中度 AD,平均年龄为 77.8 岁。采用洛顿量表在纳入时描述 6 项 BADL 的丧失模式。

结果

6 项 BADL 评分均为二进制评分,每位患者在纳入时均呈现一组丧失。对于 53%的女性,这些丧失组相互包含或完全相同,分别增加了在躯体活动、修饰、沐浴、穿衣、如厕和进食方面的丧失。对于 47%的男性,也发现了类似的顺序,其次是穿衣方面的丧失。87%的女性和 86%的男性存在丧失组的整体一致性。洛顿量表对于 AD 患者的评估非常有用。

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