Hemani Micah L, Lepor Herbert
New York University School of Medicine New York, NY.
Rev Urol. 2009 Fall;11(4):190-5.
Procedural and surgical site infections create difficult and complex clinical scenarios. A source for pathogens is often thought to be the skin surface, making skin preparation at the time of the procedure critical. The most common skin preparation agents used today include products containing iodophors or chlorhexidine gluconate. Agents are further classified by whether they are aqueous-based or alcohol-based solutions. Traditional aqueous-based iodophors, such as povidone-iodine, are one of the few products that can be safely used on mucous membrane surfaces. Alcohol-based solutions are quick, sustained, and durable, with broader spectrum antimicrobial activity. These agents seem ideal for longer open surgeries with the potential for irrigation or surgical spillage, such as cystoprostatectomy, radical prostatectomy, and retroperitoneal lymph node dissection.
手术部位感染会造成困难且复杂的临床情况。病原体的一个来源通常被认为是皮肤表面，这使得手术时的皮肤准备至关重要。如今最常用的皮肤准备剂包括含碘伏或葡萄糖酸氯己定的产品。这些制剂还可根据其是水基溶液还是醇基溶液进一步分类。传统的水基碘伏，如聚维酮碘，是少数可安全用于黏膜表面的产品之一。醇基溶液起效快、持续且持久，具有更广泛的抗菌活性。这些制剂似乎非常适合那些可能需要冲洗或手术中出现液体外溢的较长时间的开放性手术，如膀胱前列腺切除术、根治性前列腺切除术和腹膜后淋巴结清扫术。
