Department of Gynecology and Obstetrics, Hospital Rudolfstiftung, Vienna, Austria.
Arch Gynecol Obstet. 2011 Mar;283(3):525-30. doi: 10.1007/s00404-010-1368-6. Epub 2010 Jan 29.
Aim of the study was to evaluate Evra use in adolescents and compare the outcome with adult users.
A total of 80 adolescents and 178 adults were followed-up at 1-, 3-, and 6-month interval with their compliance, satisfaction, cycle control, and adverse events being assessed.
Compliance rate was generally higher among adult users (p < 0.05). Partial and complete patch detachment were both significantly higher among adolescents (p < 0.05). Self-reported side effects did not differ between both groups and declined over the time. Overall satisfaction was high among most subjects. Compared with previous contraception, most subjects reported better satisfaction with Evra (p < 0.05).
This investigation observed an overall positive impression of Evra with good compliance among adolescent and adult users. This might be an effect of the convenience of the weekly dosing schedule. Compliance is of utmost importance in teenagers as this age group is at highest risk of unintended pregnancy.
本研究旨在评估屈螺酮炔雌醇片在青少年中的应用，并将其结果与成年使用者进行比较。
共对 80 名青少年和 178 名成年使用者进行了为期 1、3 和 6 个月的随访，评估其依从性、满意度、周期控制和不良反应。
成年使用者的依从率普遍较高（p＜0.05）。青少年中部分和完全贴片脱落的发生率均显著较高（p＜0.05）。两组的自述副作用无差异，并随时间推移而下降。大多数受试者的总体满意度较高。与之前的避孕方法相比，大多数受试者报告对屈螺酮炔雌醇片的满意度更高（p＜0.05）。
本研究观察到屈螺酮炔雌醇片在青少年和成年使用者中均有良好的依从性和整体积极印象。这可能是每周给药方案的便利性的影响。在青少年中，依从性至关重要，因为该年龄段最容易出现意外怀孕。
