Ono Nobuko, Sakabe Akiko, Nakajima Masashi
Department of Neurology, Tokyo Rosai Occupational Disease and Injuries Hospital, Japan.
Brain Nerve. 2010 Jan;62(1):81-4.
We report a patient with herpes zoster oticus who presented with acute jugular foramen syndrome, and we present the review of 9 similar cases reported previously. Jugular foramen syndrome associated with varicella-zoster virus (VZV) infection is characterized by acute-onset dysphagia and dysphonia, usually accompanied or preceded by cranial, cervical, or pharyngeal pain. Herpetic eruptions on the skin or the mucosal surface may not occur, occur late after onset, or go undetected. Magnetic resonance imaging may reveal contrast enhancement around the jugular foramen, which implying inflammation of the glossopharyngeal or the vagal nerve ganglia, and its extension to the spinal root of the accessory nerve through the cerebrospinal fluid (CSF). The presence of VZV-DNA or VZV antibody in the CSF should be tested for early diagnosis and initiation of anti-viral treatment.
我们报告了一例患有耳带状疱疹并伴有急性颈静脉孔综合征的患者,并对先前报道的9例类似病例进行了回顾。与水痘-带状疱疹病毒(VZV)感染相关的颈静脉孔综合征的特征为急性吞咽困难和发音困难,通常伴有或先于头部、颈部或咽部疼痛出现。皮肤或黏膜表面可能不出现疱疹,或在发病后期出现,或未被发现。磁共振成像可能显示颈静脉孔周围有对比增强,这意味着舌咽神经或迷走神经节发炎,并通过脑脊液(CSF)延伸至副神经的脊髓根。应检测脑脊液中VZV-DNA或VZV抗体以进行早期诊断并开始抗病毒治疗。