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[早产儿医院感染的危险因素及病原菌]

[Risk factors and pathogens of nosocomial infection in preterm infants].

作者信息

Wang Yu-Hong, Xia Shi-Wen

机构信息

Department of Neonatology, Hubei Maternal and Child Health Care Hospital, Wuhan 430070, China.

出版信息

Zhongguo Dang Dai Er Ke Za Zhi. 2009 Dec;11(12):980-2.

PMID:20113603

Abstract

OBJECTIVE

To investigate the risk factors and the pathogens of nosocomial infection in preterm infants.

METHODS

The medical data of 197 preterm infants with nosocomial infection were retrospectively studied.

RESULTS

The incidence of nosocomial infection was 22.2% (197/887). Small gestational age (OR=4.125, p<0.05), low birth weight (OR=5.450, p<0.05), mechanical ventilation therapy (OR=4.435, p<0.05) and delayed enteral feedings (OR=3.765, p<0.05) were found to be important risk factors for nosocomial infection. Klebsiella was the main pathogen (22.3%), followed by Staphylococcus (18.4%).

CONCLUSIONS

Hygienic handwashing, decreasing invassive procedures and an early start of enteral feeding are crucial for preventing nosocomal infection in preterm infants. Klebsiella is the main pathogen of nosocomal infections.

摘要

目的

探讨早产儿医院感染的危险因素及病原菌。

方法

回顾性研究197例发生医院感染的早产儿的医疗资料。

结果

医院感染发生率为22.2%（197/887）。发现小胎龄（OR=4.125，p<0.05）、低出生体重（OR=5.450，p<0.05）、机械通气治疗（OR=4.435，p<0.05）和肠内喂养延迟（OR=3.765，p<0.05）是医院感染的重要危险因素。克雷伯菌是主要病原菌（22.3%），其次是葡萄球菌（18.4%）。