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父源性因素与低出生体重儿、早产儿和小于胎龄儿出生:系统评价。

Paternal factors and low birthweight, preterm, and small for gestational age births: a systematic review.

机构信息

Department of Pediatrics, Mount Sinai Hospital, and the Departments of Pediatrics and of Health Policy, Management and Evaluations, University of Toronto, Toronto, Ontario, Canada.

出版信息

Am J Obstet Gynecol. 2010 Feb;202(2):103-23. doi: 10.1016/j.ajog.2009.08.026.

DOI:10.1016/j.ajog.2009.08.026
PMID:20113689
Abstract

A systematic review of the risks of a low birthweight (LBW), preterm, and small-for-gestational-age births in relation to paternal factors was performed. Medline, Embase, Cumulative Index of Nursing and Allied Health Literature, and bibliographies of identified articles were searched for English-language studies. Study qualities were assessed according to a predefined checklist. Thirty-six studies of low-to-moderate risk of bias were reviewed for various paternal factors: age, height, weight, birthweight, occupation, education, and alcohol use. Extreme paternal age was associated with higher risk for LBW. Among infants who were born to tall fathers, birthweight was approximately 125-150 g higher compared with infants who were born to short fathers. Paternal LBW was associated with lower birthweight of the offspring. In conclusion, paternal characteristics including age, height, and birthweight are associated with LBW. Paternal occupational exposure and low levels of education may be associated with LBW; however, further studies are needed.

摘要

系统评价了与父亲因素相关的低出生体重(LBW)、早产和小于胎龄儿出生的风险。检索了 Medline、Embase、护理和联合健康文献累积索引以及已确定文章的参考文献,以获取英文研究。根据预先确定的检查表评估了研究质量。对各种父亲因素(年龄、身高、体重、出生体重、职业、教育和饮酒)的 36 项低至中度偏倚风险研究进行了审查:高龄父亲与 LBW 风险增加相关。与矮个父亲所生的婴儿相比,高个父亲所生的婴儿的出生体重大约高 125-150 克。父亲 LBW 与后代的低出生体重有关。总之,包括年龄、身高和出生体重在内的父亲特征与 LBW 有关。父亲的职业暴露和低教育水平可能与 LBW 有关;然而,还需要进一步的研究。

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