Laboratoire de Physiopathologie Orale Moléculaire, INSERM, Centre de Recherche des Cordeliers, Paris, France.
J Endod. 2010 Feb;36(2):342-4. doi: 10.1016/j.joen.2009.09.021. Epub 2009 Nov 5.
After a traumatic injury to the upper central incisors of a 7-year-old patient, avulsion of tooth #9 and pulp exposure after crown fracture of tooth #8 were managed.
After immediate replacement of tooth #9 in its socket, teeth were splinted for 3 weeks. No endodontic treatment was performed on tooth #9, but pulp capping was performed with mineral trioxide aggregate (Pro Root MTA; Dentsply Maillefer, Ballaigues, Switzerland) on #8, and both teeth were restored with composite resin. The teeth were monitored every 3 months for 2 years.
At 24 months, both teeth responded positively to electrometric tests and roots showed normal development, but an abnormal reduction in the size of the root canal space of tooth#8 was observed.
Based on these observations, we discuss odontoblast behavior in the context of the stage of dentinogenesis and the probable disturbance of regulation of the physiologic dentinogenic secretory processes in the pathologic situation.
一名 7 岁患者的上中切牙遭受创伤性损伤后,牙 9 发生脱位,牙 8 冠折并暴露牙髓。
牙 9 脱位即刻复位后,牙齿用夹板固定 3 周。未对牙 9 进行根管治疗,但对牙 8 行牙髓覆盖治疗,用矿化三氧化物凝聚体(Pro Root MTA;Dentsply Maillefer,Ballaigues,瑞士)。两颗牙齿均用复合树脂修复。在 2 年内每 3 个月监测一次牙齿。
24 个月时,两颗牙齿的电测反应均为阳性,牙根发育正常,但牙 8 的根管空间大小出现异常减小。
根据这些观察结果,我们讨论了成牙本质细胞在牙本质生成阶段的行为以及在病理情况下生理牙本质分泌过程调节可能受到的干扰。