Gearhart J P, Herzberg G Z, Jeffs R D
Department of Urology, James Buchanan Brady Urological Institute, Johns Hopkins Hospital and Children's Center, Baltimore, Maryland 21205.
Pediatrics. 1991 Apr;87(4):445-50.
Between June 1979 and June 1989, 54 children with urolithiasis were evaluated and treated at the Johns Hopkins Children's Center. The most common symptoms were flank or abdominal pain (58%) and gross hematuria (28%). In 46 children (86%), stones were secondary to a preexisting condition and in only 8 (14%) no apparent cause of stone formation could be found. Thirty-six patients (66%) had a solitary stone, most commonly found in the kidney. Urinary tract infections were present in 25 (47%) of the patients who had stones. Stones composed either of calcium oxalate or struvite were the most frequently recovered in these patients with infections. Twenty-one patients (39%) spontaneously passed their stones whereas 23 (43%) required either surgery or extracorporeal shock-wave lithotripsy to resolve stones. Ten (20%) showed recurrence of their urolithiasis, with follow-up examination periods ranging from 1 month to 10 years. Recent advances in the management of urolithiasis and their applicability to the pediatric population are discussed.
1979年6月至1989年6月期间,约翰·霍普金斯儿童中心对54例尿路结石患儿进行了评估和治疗。最常见的症状是胁腹或腹痛(58%)和肉眼血尿(28%)。46例患儿(86%)的结石继发于先前存在的疾病,只有8例(14%)未发现明显的结石形成原因。36例患者(66%)有单个结石,最常见于肾脏。25例(47%)有结石的患者存在尿路感染。在这些感染患者中,最常发现的结石成分是草酸钙或鸟粪石。21例患者(39%)结石自行排出,而23例(43%)需要手术或体外冲击波碎石术来排出结石。10例(20%)出现尿路结石复发,随访检查时间从1个月到10年不等。本文讨论了尿路结石治疗的最新进展及其在儿科患者中的适用性。