Gu W, Rice G E
Monash University Department of Obstetrics and Gynecology, Monash Medical Centre, Clayton, Vic., Australia.
Prostaglandins Leukot Essent Fatty Acids. 1991 Jan;42(1):15-8. doi: 10.1016/0952-3278(91)90060-i.
Production of prostaglandin E2 (PGE2), F2 alpha (PGF2 alpha) and 6-keto-prostaglandin F1 alpha (6-keto-PGF1 alpha) by pregnant rat uterus were measured in vitro. At mid-pregnancy, myometrium incubated with decidua attached released more prostanoids into the culture medium than when incubated without. As pregnancy progressed to 21 days more prostanoids were detected in the culture medium. However, no significantly increased conversion of exogenous arachidonic acid (AA) by myometrium was found.
体外测定了妊娠大鼠子宫中前列腺素E2（PGE2）、F2α（PGF2α）和6-酮-前列腺素F1α（6-酮-PGF1α）的产生。在妊娠中期，与附着有蜕膜的子宫肌层一起孵育时，释放到培养基中的前列腺素类物质比不与蜕膜一起孵育时更多。随着妊娠进展到21天，在培养基中检测到更多的前列腺素类物质。然而，未发现子宫肌层对外源性花生四烯酸（AA）的转化有显著增加。
