根据阿司匹林和氯吡格雷反应性分层的患者中替罗非班对血小板抑制作用的评估：3T/2R研究（对阿司匹林和/或氯吡格雷耐药患者使用替罗非班进行个体化治疗） - Suppr

Evaluation of platelet inhibition by tirofiban in patients stratified according to aspirin and clopidogrel responsiveness: the 3T/2R (Tailoring treatment with tirofiban in patients showing resistance to aspirin and/or resistance to clopidogrel).

作者信息

Campo Gianluca, Valgimigli Marco, Frangione Alice, Luccarelli Serena, Cangiano Elisa, Cavazza Caterina, Fileti Luca, Ferrari Roberto

出版信息

J Am Coll Cardiol. 2010 Jan 19;55(3):255-6. doi: 10.1016/j.jacc.2009.08.052.

DOI:10.1016/j.jacc.2009.08.052

PMID:20117406

Abstract

摘要

相似文献

Evaluation of platelet inhibition by tirofiban in patients stratified according to aspirin and clopidogrel responsiveness: the 3T/2R (Tailoring treatment with tirofiban in patients showing resistance to aspirin and/or resistance to clopidogrel).根据阿司匹林和氯吡格雷反应性分层的患者中替罗非班对血小板抑制作用的评估：3T/2R研究（对阿司匹林和/或氯吡格雷耐药患者使用替罗非班进行个体化治疗）

J Am Coll Cardiol. 2010 Jan 19;55(3):255-6. doi: 10.1016/j.jacc.2009.08.052.

Long-term clinical outcome based on aspirin and clopidogrel responsiveness status after elective percutaneous coronary intervention: a 3T/2R (tailoring treatment with tirofiban in patients showing resistance to aspirin and/or resistance to clopidogrel) trial substudy.基于择期经皮冠状动脉介入治疗后阿司匹林和氯吡格雷反应状态的长期临床结局：3T/2R（替罗非班个体化治疗阿司匹林抵抗和/或氯吡格雷抵抗患者）试验亚研究。

J Am Coll Cardiol. 2010 Oct 26;56(18):1447-55. doi: 10.1016/j.jacc.2010.03.103.

Intensifying platelet inhibition with tirofiban in poor responders to aspirin, clopidogrel, or both agents undergoing elective coronary intervention: results from the double-blind, prospective, randomized Tailoring Treatment with Tirofiban in Patients Showing Resistance to Aspirin and/or Resistance to Clopidogrel study.在对阿司匹林、氯吡格雷或两者均反应不佳且接受择期冠状动脉介入治疗的患者中，使用替罗非班强化血小板抑制：来自双盲、前瞻性、随机的“阿司匹林抵抗和/或氯吡格雷抵抗患者使用替罗非班定制治疗”研究的结果

Circulation. 2009 Jun 30;119(25):3215-22. doi: 10.1161/CIRCULATIONAHA.108.833236. Epub 2009 Jun 15.

Tailoring treatment with tirofiban in patients showing resistance to aspirin and/or resistance to clopidogrel (3T/2R). Rationale for the study and protocol design.

Cardiovasc Drugs Ther. 2008 Aug;22(4):313-20. doi: 10.1007/s10557-008-6121-z. Epub 2008 Jun 17.

Pharmacodynamics and pharmacokinetics of the platelet GPIIb/IIIa inhibitor tirofiban in patients undergoing percutaneous coronary intervention: implications for adjustment of tirofiban and clopidogrel dosage.血小板糖蛋白IIb/IIIa抑制剂替罗非班在接受经皮冠状动脉介入治疗患者中的药效学和药代动力学：对替罗非班和氯吡格雷剂量调整的意义

Thromb Res. 2005;116(1):55-66. doi: 10.1016/j.thromres.2004.11.011. Epub 2004 Dec 8.

Effect of tirofiban plus clopidogrel and aspirin on primary percutaneous coronary intervention via transradial approach in patients with acute myocardial infarction.替罗非班联合氯吡格雷及阿司匹林对急性心肌梗死患者经桡动脉途径行直接经皮冠状动脉介入治疗的影响。

Chin Med J (Engl). 2008 Mar 20;121(6):522-7.

Influence of aspirin resistance on platelet function profiles in patients on long-term aspirin and clopidogrel after percutaneous coronary intervention.经皮冠状动脉介入术后长期服用阿司匹林和氯吡格雷患者中阿司匹林抵抗对血小板功能谱的影响。

Am J Cardiol. 2006 Jan 1;97(1):38-43. doi: 10.1016/j.amjcard.2005.07.106. Epub 2005 Nov 7.

Drug therapy during percutaneous coronary interventions in stable and unstable coronary artery disease: the Italian Drug Evaluation in Angioplasty (IDEA) study.稳定型和不稳定型冠状动脉疾病经皮冠状动脉介入治疗期间的药物治疗：意大利血管成形术药物评估（IDEA）研究

Ital Heart J. 2005 Feb;6(2):106-18.

Effectiveness and safety of glycoprotein IIb/IIIa inhibitors and clopidogrel alone and in combination in non-ST-segment elevation myocardial infarction (from the National Registry of Myocardial Infarction-4).糖蛋白IIb/IIIa抑制剂与氯吡格雷单独及联合应用于非ST段抬高型心肌梗死的有效性和安全性（来自心肌梗死国家注册研究-4）

Am J Cardiol. 2006 Nov 1;98(9):1125-31. doi: 10.1016/j.amjcard.2006.05.043. Epub 2006 Aug 31.

Tirofiban optimizes platelet inhibition for immediate percutaneous coronary intervention in high-risk acute coronary syndromes.替罗非班可优化血小板抑制作用，用于高危急性冠脉综合征的直接经皮冠状动脉介入治疗。

Thromb Haemost. 2008 Oct;100(4):648-54.

引用本文的文献

Propensity score-adjusted analysis on early tirofiban administration to prevent thromboembolic complications during stand-alone coil embolization of ruptured aneurysms.倾向性评分调整分析早期替罗非班给药在单独使用弹簧圈栓塞破裂动脉瘤中预防血栓栓塞并发症。

Sci Rep. 2024 Nov 1;14(1):26350. doi: 10.1038/s41598-024-77354-1.

Ticagrelor and preconditioning in patients with stable coronary artery disease (TAPER-S): a randomized pilot clinical trial.替格瑞洛与稳定型冠状动脉疾病患者的预处理（TAPER-S）：一项随机先导临床试验。

Trials. 2020 Feb 17;21(1):192. doi: 10.1186/s13063-020-4116-7.

Platelet Aggregometry Testing: Molecular Mechanisms, Techniques and Clinical Implications.血小板聚集检测：分子机制、技术及临床意义

Int J Mol Sci. 2017 Aug 18;18(8):1803. doi: 10.3390/ijms18081803.

Efficacy and safety of individually tailored antiplatelet therapy in patients with acute coronary syndrome after coronary stenting: a single center, randomized, feasibility study.经皮冠状动脉介入治疗术后急性冠状动脉综合征患者个体化抗血小板治疗的疗效和安全性：一项单中心、随机、可行性研究。

J Geriatr Cardiol. 2015 Jan;12(1):23-9. doi: 10.11909/j.issn.1671-5411.2015.01.003.

Triple antiplatelet therapy in acute coronary syndromes.急性冠脉综合征的三联抗血小板治疗。

Drugs. 2011 Sep 10;71(13):1703-19. doi: 10.2165/11594100-000000000-00000.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Evaluation of platelet inhibition by tirofiban in patients stratified according to aspirin and clopidogrel responsiveness: the 3T/2R (Tailoring treatment with tirofiban in patients showing resistance to aspirin and/or resistance to clopidogrel).

作者信息

出版信息

相似文献

引用本文的文献

文献检索

文件翻译

深度研究

Suppr 超能文献

相似文献

引用本文的文献