Institute of Computer Science, University of Rostock, Rostock, Germany.
Brief Bioinform. 2010 May;11(3):290-300. doi: 10.1093/bib/bbp067. Epub 2010 Jan 28.
Dry-lab experimentation is being increasingly used to complement wet-lab experimentation. However, conducting dry-lab experiments is a challenging endeavor that requires the combination of diverse techniques. JAMES II, a plug-in-based open source modeling and simulation framework, facilitates the exploitation and configuration of these techniques. The different aspects that form an experiment are made explicit to facilitate repeatability and reuse. Each of those influences the performance and the quality of the simulation experiment. Common experimentation pitfalls and current challenges are discussed along the way.
干实验越来越多地被用于补充湿实验。然而,进行干实验是一项具有挑战性的工作,需要结合多种技术。JAMES II 是一个基于插件的开源建模和模拟框架,它促进了这些技术的利用和配置。实验的不同方面被明确表示,以促进可重复性和可重用性。这些都会影响模拟实验的性能和质量。在这个过程中,讨论了常见的实验陷阱和当前的挑战。