Schlumpf U
Medizinische Klinik, Kantonsspital Luzern.
Ther Umsch. 1991 Jan;48(1):34-41.
The inflammatory stage of osteoarthritis when secondary synovitis contributes to the characteristic clinical presentation is first explained. During episodes of acute synovitis nonsteroidal antiinflammatory drugs may be particularly beneficial. Guidelines for a prescribing policy are given in which a safety first approach is adopted. Propionic acid derivatives or newer drugs with similar properties are proposed as initial therapy to control symptoms of osteoarthritis. Special problems of patients at risk (ulcer patients, renal insufficiency, heart failure) are considered.
首先解释了骨关节炎的炎症阶段，此时继发性滑膜炎导致了其典型的临床表现。在急性滑膜炎发作期间，非甾体抗炎药可能特别有益。给出了一种开药政策指南，其中采用了安全第一的方法。建议使用丙酸衍生物或具有类似性质的新药作为控制骨关节炎症状的初始治疗。还考虑了高危患者（溃疡患者、肾功能不全患者、心力衰竭患者）的特殊问题。
