重新探讨急性抗精神病药诱发的静坐不能。
Acute antipsychotic-induced akathisia revisited.
出版信息
Br J Psychiatry. 2010 Feb;196(2):89-91. doi: 10.1192/bjp.bp.109.070540.
PMID:20118449
Abstract
Akathisia remains one of the most prevalent and distressful antipsychotic-induced adverse events. Effective and well-tolerated treatment is a major unmet need in akathisia that merits a search for new remedies. Accumulating evidence indicates that agents with marked serotonin-2A receptor antagonism may represent a new class of potential anti-akathisia treatment.
摘要
静坐不能仍是最普遍和最痛苦的抗精神病药诱发的不良反应之一。有效的、耐受性良好的治疗是静坐不能的一个主要未满足的需求，值得寻找新的治疗方法。越来越多的证据表明，具有显著 5-羟色胺 2A 受体拮抗作用的药物可能代表一类新的潜在抗静坐不能治疗药物。
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