Izumi Kouji, Mizokami Atsushi, Namiki Mikio
Department of Integrative Cancer Therapy and Urology, Kanazawa University Graduate School of Medical Science.
Clin Calcium. 2010 Feb;20(2):175-81.
The incidence of prostate cancer is increasing and the patients are generally of relatively advanced age. There has been an increase in the use of hormonal therapy in such cases. However, hormonal therapy for prostate cancer increases the risk of fracture. Bisphosphonates have been reported to prevent the bone loss caused by hormonal therapy. Therefore, oral bisphosphonates will play an important role in preventing bone loss in prostate cancer patients undergoing hormonal therapy.
前列腺癌的发病率正在上升,且患者通常年龄相对较大。在这类病例中,激素疗法的使用有所增加。然而,前列腺癌的激素疗法会增加骨折风险。据报道,双膦酸盐可预防激素疗法引起的骨质流失。因此,口服双膦酸盐在预防接受激素疗法的前列腺癌患者骨质流失方面将发挥重要作用。