Public Health Agency of Canada, Ottawa, Canada. Lily_Fang@phac- aspc.gc.ca
Sex Transm Dis. 2010 Jan;37(1):18-25. doi: 10.1097/OLQ.0b013e3181b617dc.
The objective was to determine trends in age disparities between reported rates of chlamydia, gonorrhea, and infectious syphilis among younger versus middle-age Canadians.
We examined age- and sex-specific reported rates of chlamydia, gonorrhea, and infectious syphilis between 1997 and 2007. Sexually transmitted infection (STI) rates in the younger age group (15-29 years) were compared to the middle-age group (40-59 years) over the 11-year period. We used Poisson regression to examine trends in age-specific (younger:middle-age) rate ratios.
Between 1997 and 2007, both the number and rate of reported cases increased for all 3 nationally notifiable STIs. Although chlamydia and gonorrhea rates continued to be higher among younger adults, rates of all 3 STIs increased more dramatically among middle-age adults. Between 1997 and 2007, chlamydia rates increased by 86.8% among adults aged 15 to 29 (P <0.0001) and 165.9% among adults 40- to 59-years-old (P <0.0001). The corresponding increases for gonorrhea were 133.3% (P <0.0001) and 210.2% (P <0.0001) respectively. Infectious syphilis rates increased 5-fold among younger adults compared to an increase of 11-fold among middle-age adults (P <0.0001) since 1997. The reported rate ratios (younger:middle-age) decreased over time for chlamydia (P <0.0001), gonorrhea (P <0.0001), and syphilis (P = 0.005). Males were disproportionately represented among reported chlamydia, gonorrhea, and infectious syphilis cases, constituting 59.8%, 87.6%, and 93.0% of middle-age adult cases, respectively, in 2007.
Middle-age adults may be increasingly affected by chlamydia, gonorrhea and infectious syphilis. There is a need for sexual health information targeting Canada's middle-age adults and their health care providers.
本研究旨在确定加拿大年轻人与中年人衣原体、淋病和传染性梅毒报告发病率之间的年龄差距趋势。
我们检测了 1997 年至 2007 年间按年龄和性别分类的衣原体、淋病和传染性梅毒的报告发病率。在 11 年期间，将年轻组（15-29 岁）的性传播感染（STI）率与中年组（40-59 岁）进行比较。我们使用泊松回归检验年龄特异性（年轻组：中年组）率比的趋势。
在这三种国家法定 STI 中，1997 年至 2007 年间报告的病例数量和发病率均有所增加。尽管年轻人的衣原体和淋病发病率仍然较高，但所有三种 STI 的发病率在中年人群中增加更为显著。1997 年至 2007 年间，15 至 29 岁成年人的衣原体发病率增加了 86.8%（P<0.0001），40 至 59 岁成年人的发病率增加了 165.9%（P<0.0001）。淋病的相应增长率分别为 133.3%（P<0.0001）和 210.2%（P<0.0001）。自 1997 年以来，年轻人的传染性梅毒发病率增加了 5 倍，而中年人的发病率增加了 11 倍（P<0.0001）。1997 年以来，报告的率比（年轻组：中年组）随时间推移下降，衣原体（P<0.0001）、淋病（P<0.0001）和梅毒（P=0.005）均呈下降趋势。在 2007 年，男性在衣原体、淋病和传染性梅毒报告病例中占不成比例，分别占中年组病例的 59.8%、87.6%和 93.0%。
中年人群可能越来越受到衣原体、淋病和梅毒的影响。需要为加拿大的中年人群及其卫生保健提供者提供性健康信息。
