Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
Cornea. 2010 Mar;29(3):269-71. doi: 10.1097/ICO.0b013e3181b6104e.
To determine the clinical profile, demographic characteristics, and socioeconomic status in patients with bilateral blinding corneal disease who are waiting for keratoplasty.
Patients with bilateral blindness from corneal diseases, who were admitted for keratoplasty in the cornea services of a tertiary eye care center in Northern India from May 1, 2004, to December 31, 2004, were enrolled in the study. The clinical presentation, demographic details, and socioeconomic status of the patients were noted and analyzed.
Fifty-nine patients with bilateral blindness from corneal disease were included in the study, of which 56 (95%) had bilateral corneal disease resulting from similar etiology and three (5%) of different etiology in both eyes. Twenty-two patients (37%) had simultaneous onset and 37 patients (63%) had separate onset of the corneal disease with subsequent involvement of the fellow eye and a mean interval of 16.4 years. Infection was the predominant etiologic diagnosis in patients with bilateral similar etiologic disease (62.5%). The pinhole visual acuity was 1/60 or less in the better eye in 45 patients and 1/60 to 3/60 in eight and 3/60 to 6/60 in six patients. Fifty-four patients (92%) lived in rural areas, whereas only five patients (8%) lived in urban areas. Only 18 patients (31 %) were gainfully employed. Thirty patients (51 %) were illiterate.
Corneal infection is the most common cause of bilateral corneal blindness. There is a high frequency of involvement of one eye with subsequent involvement of the other eye at a later date. This is more commonly seen in the rural population, particularly in those belonging to a lower socioeconomic stratum and those who are illiterate and tend to be ignorant about proper eye care.
确定等待角膜移植的双侧盲性角膜疾病患者的临床特征、人口统计学特征和社会经济地位。
本研究纳入了 2004 年 5 月 1 日至 2004 年 12 月 31 日期间在印度北部一家三级眼科中心的角膜科就诊的双侧盲性角膜疾病患者。记录并分析了患者的临床表现、人口统计学细节和社会经济状况。
本研究共纳入了 59 例双侧盲性角膜疾病患者，其中 56 例（95%）双眼均患有由相同病因引起的角膜疾病，3 例（5%）双眼的病因不同。22 例（37%）患者双眼同时发病，37 例（63%）患者双眼先后发病，随后对侧眼受累，平均间隔时间为 16.4 年。感染是双侧病因相同的患者中最常见的病因诊断（62.5%）。45 例患者的健眼视力为针孔视力 1/60 或更差，8 例患者为 1/60 至 3/60，6 例患者为 3/60 至 6/60。54 例患者（92%）生活在农村地区，而只有 5 例患者（8%）生活在城市地区。仅有 18 例患者（31%）有固定收入。30 例患者（51%）为文盲。
角膜感染是双侧角膜盲的最常见原因。一眼受累后，随后另一眼在后期受累的频率较高。这种情况在农村人口中更为常见，特别是在社会经济地位较低、文盲且对眼部护理认识不足的人群中更为常见。
