Department of Pediatrics, Fukushima Medical University of School of Medicine 1 Hikarigaoka, Fukushima, Japan.
J Perinatol. 2010 Feb;30(2):146-8. doi: 10.1038/jp.2009.111.
The incidence of measles epidemics has decreased recently owing to the development and widespread use of measles vaccine in the United States of America and Europe. However, repeated measles epidemics have been reported in Japan. Here, the authors report a case of an extremely low body weight infant (ELBWI) whose mother had a measles virus infection. Real-time PCR was performed on the infant's blood and urine samples and skin, nasal secretion, and anal swabs, as well as on the mother's breast milk, blood samples and throat swabs. The infant was found to be positive for measles virus by PCR, but not immunoglobulin M positive. An earlier report showed that there were no such cases in which the patient was found to be positive for measles virus by real-time PCR but was not infected by the measles virus.
由于麻疹疫苗在美国和欧洲的开发和广泛使用，最近麻疹疫情的发病率有所下降。然而，在日本仍有麻疹疫情的反复报告。在这里，作者报告了一例极低出生体重儿（ELBWI）的病例，其母亲患有麻疹病毒感染。对婴儿的血液和尿液样本以及皮肤、鼻分泌物和肛门拭子，以及母亲的母乳、血液样本和咽喉拭子进行了实时 PCR 检测。婴儿的麻疹病毒 PCR 检测结果为阳性，但免疫球蛋白 M 检测结果为阴性。之前的一份报告表明，尚无此类病例，即实时 PCR 检测结果为麻疹病毒阳性但未感染麻疹病毒。
