Department of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Germany.
Soc Psychiatry Psychiatr Epidemiol. 2011 Feb;46(2):159-65. doi: 10.1007/s00127-010-0181-7. Epub 2010 Feb 2.
Relatively few studies have examined how patients with schizophrenia and depression view psychiatric research and what influences their readiness to participate.
A total of 763 patients (48% schizophrenia, 52% depression) from 7 European countries were examined using a specifically designed self-report questionnaire ["Hamburg Attitudes to Psychiatric Research Questionnaire" (HAPRQ)].
Most patients (98%) approved of psychiatric research, in general, at least "a little". There was a tendency to approve psychosocial rather than biological research topics (e.g. research on the role of the family by 91% of patients compared to 79% in genetics). Reasons to participate were mainly altruistic. Only a minority (28%) considered monetary incentives important. Patients wanted extensive background information and a feedback of the results; both were significantly more expressed by schizophrenia as compared to depressive patients, although these findings need to be interpreted with care because of age and gender differences between the diagnostic groups.
While patients expressed discerning views of psychiatric research, only few differences were apparent between the two diagnostic groups. Patients' research priorities are not the same as those of many professionals and funding bodies. Their demonstrated critical appraisal should inform future research ensuring an increased patient role in the research process.
很少有研究探讨精神分裂症和抑郁症患者如何看待精神科研究，以及哪些因素影响他们参与研究的意愿。
本研究共纳入来自 7 个欧洲国家的 763 名患者（48%为精神分裂症，52%为抑郁症），使用专门设计的自我报告问卷[“汉堡精神科研究态度问卷”（HAPRQ）]进行评估。
大多数患者（98%）至少“有点”认可一般的精神科研究。他们倾向于认可心理社会而非生物学研究课题（例如，91%的患者对家庭作用的研究，而在遗传学方面为 79%）。参与研究的主要动机是利他主义。只有少数患者（28%）认为金钱激励很重要。患者希望获得广泛的背景信息和研究结果反馈；与抑郁症患者相比，精神分裂症患者更强烈地表达了这两种需求，尽管由于诊断组之间的年龄和性别差异，这些发现需要谨慎解释。
尽管患者对精神科研究表达了有见地的观点，但在这两种诊断组之间几乎没有明显差异。患者的研究重点与许多专业人员和资助机构不同。他们表现出的批判性评价应指导未来的研究，以确保患者在研究过程中发挥更大的作用。
