克鲁肯伯格瘤
Krukenberg's tumour.
作者信息
Mijinyawa M S, Sani M U, Yusuf S M, Mohammed A Z, Alhassan S U
机构信息
Department of Medicine, Aminu Kano Teaching Hospital P.M.B. 3452, Kano, Nigeria.
出版信息
Niger J Med. 2009 Oct-Dec;18(4):416-9. doi: 10.4314/njm.v18i4.51255.
BACKGROUND
Krukenburg's tumour, a metastatic cancer to the ovary can pose difficulties in early diagnosis. The paucity of reports from our environment coupled with the difficulties we encountered makes it imperative that we report this case.
METHODS
We present a 32-year-old lady who presented with mucoid and bloody diarrhoea associated with menstrual irregularity, weight loss and lower abdominal pains 2 years after surgical treatment for gastric cancer. Literature on Krukenburg's tumour was also reviewed.
RESULTS
While serum level of CEA was found to be elevated and colonoscopy showed an ulcerated mass obliterating the lumen of the sigmoid colon, abdominal CT scan revealed bilateral adnexal masses. The histology of the colonic lesion showed signet ring carcinoma while the enlarged ovaries turned out to have evidence of metastatic adenocarcinoma.
CONCLUSION
Early diagnosis of KT can be difficult. Periodic surveillance is, therefore, essential especially in those who have had a gastrointestinal malignancy.
背景
库肯勃瘤，一种转移至卵巢的癌症，早期诊断可能存在困难。我们所在地区相关报道较少，加之我们遇到了一些困难，因此有必要报告此病例。
方法
我们报告一名32岁女性，她在胃癌手术治疗2年后出现黏液性和血性腹泻，伴有月经不调、体重减轻和下腹部疼痛。同时对库肯勃瘤的文献进行了综述。
结果
虽然发现癌胚抗原（CEA）血清水平升高，结肠镜检查显示乙状结肠腔内有一溃疡性肿物阻塞管腔，但腹部CT扫描显示双侧附件有肿物。结肠病变的组织学检查显示印戒细胞癌，而增大的卵巢经检查证实有转移性腺癌的证据。
结论
库肯勃瘤的早期诊断可能存在困难。因此，定期监测至关重要，尤其是对于那些有胃肠道恶性肿瘤病史的患者。
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