[Nitric monoxide and other indicators of free radical processes and antioxidant system in patients with mixed or monoinvasion of Opisthorhis and Metorchis].

As compared with healthy individuals, patients with mixed Opisthorhis and Metorchis invasion and/or Opisthorhis monoinvasion were found to have a considerable increase in the serum levels of nitric monoxide and malondialdehyde with the concurrent suppression of catalase activity and lipid antioxidant activity, which correlated with the blood accumulation of some toxic trace elements. The highest accumulation levels of toxic trace elements, as well as the indicators of free radical processes were detected in patients with the mixed invasion as compared with the Opisthorhis monoinvasion group, which appears to be directly related to the intensity of invasion.