Trninić Zoran, Vidacak Ana, Vrhovac Jasna, Petrov Bozo, Setka Violeta
Surgery Clinic, University Clinical Hospital Mostar, Mostar, Bosnia and Herzegovina.
Coll Antropol. 2009 Dec;33 Suppl 2:1-5.
Quality of life (QoL) has become an important outcome measure for patients with cancer, but results from population-based studies are infrequently published. The objective of this study was to asses QoL in patients who underwent the colorectal cancer (CRC) surgery and to compare it to the QoL of general population. The patients who were admitted from January 2004 until May 2006 at the Department of Gastrointestinal Surgery at the Clinical Hospital Mostar, Bosnia and Herzegovina were divided in three groups: group of CRC patients who had received surgery and as a result of surgical treatment have colostomy, group of CRC patients who had received surgery in the same period and don't have colostomy and the third group that consisted of controls. QLQ-C30 and QLQ-CR38 questionnaires by the European Organization for Cancer Research and Treatment (EORTC) were used. A total of 67 patients were included in this study, supplemented by the thirty healthy examinees. Healthy group had significantly better results in physical functioning compared with colorectal cancer patients and better results in cognitive and social functioning. Also, they reported symptoms of diarrhea and constipation less frequently than the group with colostomy and. The group with colostomy had poorer results in emotional functioning than the group without colostomy, and also reported significantly poorer results for domain "body image". Healthy group showed better results in sexual enjoinment than the patient with colorectal cancer. Patients without colostomy reported more micturition and defecation problems and female sexual problems compared to the healthy group. Generally we found that healthy population had better results than the CRC patients, while the patients with stoma had worse results than the nonstoma patients. The results presented here suggest that psychological treatment should be an integral part of the CRC treatment plan.
生活质量（QoL）已成为癌症患者的一项重要疗效指标，但基于人群的研究结果却很少发表。本研究的目的是评估接受结直肠癌（CRC）手术患者的生活质量，并将其与普通人群的生活质量进行比较。2004年1月至2006年5月在波斯尼亚和黑塞哥维那莫斯塔尔临床医院胃肠外科住院的患者被分为三组：接受手术且因手术治疗而有结肠造口的CRC患者组、同期接受手术但没有结肠造口的CRC患者组以及由对照组组成的第三组。使用了欧洲癌症研究与治疗组织（EORTC）的QLQ-C30和QLQ-CR38问卷。本研究共纳入67例患者，并补充了30名健康受试者。与结直肠癌患者相比，健康组在身体功能方面的结果明显更好，在认知和社会功能方面也有更好的结果。此外，他们报告腹泻和便秘症状的频率低于有结肠造口的组。有结肠造口的组在情感功能方面的结果比没有结肠造口的组差，并且在“身体形象”领域的结果也明显更差。健康组在性享受方面的结果比结直肠癌患者更好。与健康组相比，没有结肠造口的患者报告了更多的排尿和排便问题以及女性性功能问题。总体而言，我们发现健康人群的结果比CRC患者更好，而有造口的患者比没有造口的患者结果更差。这里呈现的结果表明，心理治疗应该成为CRC治疗计划的一个组成部分。
