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正己烷及其毒理学效应:综述。

N-hexane and its toxicologic effects: a review.

机构信息

Occupational Medicine Department of the Labour Inspection Service, Copenhagen, Denmark.

出版信息

Scand J Work Environ Health. 1981 Sep;7(3):157-68. doi: 10.5271/sjweh.3107.

DOI:10.5271/sjweh.3107
PMID:20120580
Abstract

This review is a critical survey and evaluation of the recent literature relevant as medical background for a discussion of hygienic threshold values for hexane. Polyneuropathy and maculopathy, as well as subclinical effects, e.g., functional disturbances (conduction velocity of the motor and sensory nerves), are included.

摘要

这篇综述是对近期相关文献的批判性调查和评估,这些文献是讨论己烷卫生阈值的医学背景的重要依据。包括多发性神经病和黄斑病变,以及亚临床效应,例如功能障碍(运动和感觉神经的传导速度)。

相似文献

1
N-hexane and its toxicologic effects: a review.正己烷及其毒理学效应:综述。
Scand J Work Environ Health. 1981 Sep;7(3):157-68. doi: 10.5271/sjweh.3107.
2
N-hexane neuropathy in screen printers.丝网印刷工人中的正己烷神经病变
Electromyogr Clin Neurophysiol. 2007 May-Jun;47(3):145-52.
3
Occupational ototoxicity of n-hexane.正己烷的职业性耳毒性
Hum Exp Toxicol. 2008 Jun;27(6):471-6. doi: 10.1177/0960327108093719.
4
[Polyneuropathy caused by n-hexane].
Rev Clin Esp. 1981 May 31;161(4):257-8.
5
[Neuropathy by n-hexanes: a generalized disorder of the intermediate filaments].[正己烷所致神经病:中间丝的全身性疾病]
Neurologia. 1998 Nov;13(9):417-21.
6
Impairment of colour vision in patients with n-hexane exposure-dependent toxic polyneuropathy.
Occup Med (Lond). 2002 Jun;52(4):183-6. doi: 10.1093/occmed/52.4.183.
7
Polyneuropathy due to glue exposure: case report and 16-year follow-up.因接触胶水导致的多发性神经病:病例报告及16年随访
Arch Phys Med Rehabil. 1986 Nov;67(11):827-8.
8
[Occupational N-hexane neuropathy: clinical and neurophysiological investigation].[职业性正己烷神经病:临床与神经生理学研究]
Med Pr. 1999;50(1):31-6.
9
Modification of metabolism and neurotoxicity of hexane by co-exposure of toluene.
Int Arch Occup Environ Health. 1993;65(1 Suppl):S227-30. doi: 10.1007/BF00381347.
10
Limitations of occupational air contaminant standards, as exemplified by the neurotoxin N-hexane.职业空气污染物标准的局限性,以神经毒素正己烷为例。
J Public Health Policy. 1999;20(4):441-58.

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Bone marrow mesenchymal stem cells promote remyelination in spinal cord by driving oligodendrocyte progenitor cell differentiation via TNFα/RelB-Hes1 pathway: a rat model study of 2,5-hexanedione-induced neurotoxicity.骨髓间充质干细胞通过 TNFα/RelB-Hes1 通路促进少突胶质前体细胞分化,从而促进脊髓髓鞘再生:2,5-己二酮诱导神经毒性的大鼠模型研究。
Stem Cell Res Ther. 2021 Aug 4;12(1):436. doi: 10.1186/s13287-021-02518-z.
5
Petroleum hydrocarbon toxicity in vitro: effect of n-alkanes, benzene and toluene on pulmonary alveolar macrophages and lysosomal enzymes of the lung.体外石油烃毒性:正构烷烃、苯和甲苯对肺泡巨噬细胞及肺溶酶体酶的影响
Arch Toxicol. 1987 Apr;59(6):402-7. doi: 10.1007/BF00316205.