Chhabra S, Venkatraman S
Department of Obstetrics and Gynaecology, Mahatma Gandhi Institute of Medical Sciences, Sevagram 442 102, Wardha, Maharashtra, India.
J Obstet Gynaecol. 2010 Jan;30(1):41-5. doi: 10.3109/01443610903294154.
The present study was done to show the incidence of polycystic ovarian syndrome (PCOS) in rural young women with menstrual irregularities and the correlation with different variables. During the study period, 19,339 women had attended as a gynaecological outpatient unit. A total of 9,096 (47%) of them were of 15-34 years age, of whom 1,182 (13%) had menstrual disturbances. Out of the 1,182 young women, 216 were the study subjects as per inclusion-exclusion criteria, but only 200 could be studied. After complete clinical, ultrasonographic and biochemical evaluation, it was revealed that PCOS is common in rural young women of low socioeconomic class. Such women presenting with menstrual irregularities need to be investigated for the presence of other endocrine disorders which may be present with or without PCOS. PCOS was diagnosed in 100 (50%) women. Of the 100 without PCOS, five had thyroid disorders and of the other 95, 49 (51%) had polycystic ovaries on sonography. Significantly more study objects had a family history of hypertension, diabetes and menstrual irregularities in their mothers. A state of hyperinsulinaemia indicated by a low fasting glucose to insulin ratio was present, even in non-obese women with PCOS.
本研究旨在揭示农村月经不调年轻女性多囊卵巢综合征(PCOS)的发病率及其与不同变量的相关性。在研究期间,19339名女性到妇科门诊就诊。其中共有9096名(47%)年龄在15 - 34岁之间,其中1182名(13%)有月经紊乱。在这1182名年轻女性中,根据纳入 - 排除标准,216名是研究对象,但最终仅对200名进行了研究。经过全面的临床、超声和生化评估,发现PCOS在社会经济地位较低的农村年轻女性中很常见。此类月经不调的女性需要接受检查,以确定是否存在可能与PCOS并存或不并存的其他内分泌疾病。100名(50%)女性被诊断为PCOS。在未患PCOS的100名女性中,5名有甲状腺疾病,在另外95名中,49名(51%)超声检查显示有多囊卵巢。研究对象中,其母亲有高血压、糖尿病和月经不调家族史的明显更多。即使在非肥胖的PCOS女性中,也存在空腹血糖与胰岛素比值低所表明的高胰岛素血症状态。