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一名白人患者罹患罕见脂蛋白肾小球病:该疾病在亚洲较为多见,但在白种人群中罕见。

A rare case of lipoprotein glomerulopathy in a white man: an emerging entity in Asia, rare in the white population.

机构信息

Department of Pathology, University of Illinois, 835 S Wood St, Chicago, IL 60612, USA.

出版信息

Arch Pathol Lab Med. 2010 Feb;134(2):279-82. doi: 10.5858/134.2.279.

DOI:10.5858/134.2.279
PMID:20121619
Abstract

Lipoprotein glomerulopathy is a rare entity that predominantly affects the Asian population, mainly the Japanese and Chinese. Lipoprotein glomerulopathy is clinically characterized by proteinuria and progression to renal failure and is caused by glomerular lipoprotein thrombi formation in association with increased levels of serum apolipoprotein E. The disease has a male predominance and can affect virtually any age group. We describe the third reported case, to our knowledge, of lipoprotein glomerulopathy to affect a white patient.

摘要

脂蛋白肾小球病是一种罕见的疾病,主要影响亚洲人群,主要是日本人及中国人。脂蛋白肾小球病的临床特征为蛋白尿和进展为肾衰竭,其病因是与血清载脂蛋白 E 水平升高相关的肾小球脂蛋白血栓形成。该病以男性为主,几乎可影响任何年龄组的人群。据我们所知,我们描述了第三例脂蛋白肾小球病白人患者。

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Can J Kidney Health Dis. 2019 Jun 27;6:2054358119859576. doi: 10.1177/2054358119859576. eCollection 2019.