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外耳道血管肉瘤:一例报告

Angiosarcoma of the external ear: a case report.

作者信息

Leighton S E, Levine T P

机构信息

ENT Department, St. Mary's Hospital, London, England.

出版信息

Am J Otol. 1991 Jan;12(1):54-6.

PMID:2012191
Abstract

A case of an angiosarcoma of the pinna in an 82-year-old male is reported. Variability of presentation and lack of clinical awareness may result in a delay in the diagnosis of this rare tumor. Initial confusion may arise because of the deceptively benign clinical appearance of the lesion, which may resemble a bruise or superficial infection. Early biopsy is mandatory in view of the prognostic significance of tumor diameter at the time of diagnosis. Untreated, the mean survival of patients with angiosarcoma is 7 months. This increases to 15 to 20 months in treated patients, 12 percent being alive at 5 years. A combination of surgery and radiotherapy offers the best chance of cure. The need for wide local treatment of apparently normal tissue has been advocated because of imperceptible local spread of the tumor. Apparent cure may be followed by late local recurrence or distant metastasis, so lifelong follow-up is necessary.

摘要

报告了一例82岁男性耳廓血管肉瘤病例。临床表现的多样性以及临床意识的缺乏可能导致这种罕见肿瘤的诊断延迟。最初可能会出现混淆,因为病变看似良性的临床表现可能类似于瘀伤或浅表感染。鉴于诊断时肿瘤直径的预后意义,早期活检是必要的。未经治疗,血管肉瘤患者的平均生存期为7个月。接受治疗的患者生存期可延长至15至20个月,5年生存率为12%。手术和放疗联合应用提供了最佳的治愈机会。由于肿瘤难以察觉的局部扩散,有人主张对明显正常的组织进行广泛的局部治疗。表面上的治愈可能会随后出现局部复发或远处转移,因此需要终身随访。

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