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在一项针对11至12岁芬兰学童的为期3.4年的随机临床试验中,一种实验性龋齿控制方案的成本效益。

Cost-effectiveness of an experimental caries-control regimen in a 3.4-yr randomized clinical trial among 11-12-yr-old Finnish schoolchildren.

作者信息

Hietasalo Pauliina, Seppä Liisa, Lahti Satu, Niinimaa Ahti, Kallio Jouko, Aronen Pasi, Sintonen Harri, Hausen Hannu

机构信息

Department of Community Dentistry, University of Oulu, Oulu, Finland.

出版信息

Eur J Oral Sci. 2009 Dec;117(6):728-33. doi: 10.1111/j.1600-0722.2009.00687.x.

Abstract

The aim of this study was to assess the cost-effectiveness of an experimental caries-control regimen in a randomized clinical trial (RCT) conducted in Pori, Finland, in 2001-2005. Children (n = 497) who were 11-12 yr of age and had at least one active initial caries lesion at baseline were studied. The children in the experimental group (n = 250) were offered an individually designed patient-centered regimen for caries control. The children in the control group (n = 247) received standard dental care. Furthermore, the whole population was exposed to continuous community-level oral health promotion. Individual costs of treatment procedures and outcomes (DMFS increment score) for the follow-up period of 3.4 yr were calculated for each child in both groups. The incremental cost-effectiveness ratio was euro 34.07 per averted DMF surface. The experimental regimen was more effective, and also more costly. However, the total costs decreased year after year, and for the last 2 yr the experimental regimen was less expensive than the standard dental care. The experimental regimen would probably have been more cost-effective than standard dental care if the follow-up period had been longer, the regimen less comprehensive, and/or if dental nurses had conducted the preventive procedures.

摘要

本研究的目的是在2001年至2005年于芬兰波里进行的一项随机临床试验(RCT)中,评估一种实验性龋齿控制方案的成本效益。研究对象为11至12岁、基线时至少有一处活动性初始龋损的儿童(n = 497)。实验组(n = 250)的儿童接受了个性化设计的以患者为中心的龋齿控制方案。对照组(n = 247)的儿童接受标准牙科护理。此外,全体人群都接受了持续的社区层面口腔健康促进措施。计算了两组中每个儿童在3.4年随访期内治疗程序的个体成本和结果(DMFS增量评分)。每避免一个DMF面的增量成本效益比为34.07欧元。实验方案更有效,但成本也更高。然而,总成本逐年下降,在最后两年,实验方案比标准牙科护理成本更低。如果随访期更长、方案更不全面,和/或如果由牙科护士实施预防程序,实验方案可能会比标准牙科护理更具成本效益。

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