Boston University Medical Center, Boston, MA 02118, USA.
J Am Geriatr Soc. 2009 Nov;57 Suppl 2(Suppl 2):S259-61. doi: 10.1111/j.1532-5415.2009.02506.x.
Age is the most important risk factor for breast cancer; age is also a risk factor for undermanagement of breast cancer. One thousand eight hundred fifty-nine women aged 65 and older with early-stage breast cancer were studied, and it was found that undermanagement is a risk factor for recurrence and for dying of breast cancer. Although conservative treatment is probably warranted in patients with tumors having excellent prognostic characteristics and in women with limited life expectancies, standard treatment is needed for the majority of older women if the disproportionate burden of breast cancer in this age group is to be reduced. Better strategies are needed for identifying those most likely to benefit from standard treatment and from systematic surveillance for recurrence. In this regard, collaboration between oncologists and primary care physicians is essential for achieving high-quality care and outcomes in this vulnerable group of patients.
年龄是乳腺癌的最重要的危险因素;年龄也是乳腺癌管理不足的一个危险因素。研究了 1859 名年龄在 65 岁及以上的早期乳腺癌女性,发现管理不足是癌症复发和因乳腺癌死亡的一个危险因素。虽然对于肿瘤预后良好且预期寿命有限的患者,保守治疗可能是合理的,但如果要减少这一年龄组乳腺癌不成比例的负担,那么大多数老年女性需要接受标准治疗。需要更好的策略来确定最有可能从标准治疗和系统复发监测中获益的患者。在这方面,肿瘤学家和初级保健医生之间的合作对于为这一脆弱患者群体提供高质量的护理和结果是至关重要的。