Specht Lena
Kobenhavns Universitet, Onkologisk Klinik, Rigshospitalet, DK-2100 København Ø, Denmark.
Ugeskr Laeger. 2010 Feb 1;172(5):376-9.
Radiotherapy for cancer previously employed large treatment fields whereby cures were obtained. However, long-term follow-up documented serious long-term complications due to irradiation of normal tissues. Modern technology makes it possible to very accurately shape the high-dose volume. However, new problems emerge. Organ movement must be managed and the precise definition of the extent of the tumour tissue is crucial. Positron emission tomography and magnetic resonance imaging are increasingly used. Biological imaging may enable us to image tumour biology more accurately and modify radiation doses accordingly.
癌症放疗过去采用大的治疗野从而实现治愈。然而,长期随访记录了因正常组织受照射而出现的严重长期并发症。现代技术使得精确塑造高剂量区域成为可能。然而,新的问题也随之出现。必须控制器官运动,并且肿瘤组织范围的精确定义至关重要。正电子发射断层扫描和磁共振成像的应用越来越广泛。生物成像或许能使我们更精确地对肿瘤生物学进行成像,并据此调整放射剂量。