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北非地区哮喘的流行情况:马格里布地区哮喘见解和现实(AIRMAG)研究。

Prevalence of asthma in North Africa: the Asthma Insights and Reality in the Maghreb (AIRMAG) study.

机构信息

Mustapha Hospital, Algiers, Algeria.

出版信息

Respir Med. 2009 Dec;103 Suppl 2:S2-11. doi: 10.1016/S0954-6111(09)70022-8.

Abstract

BACKGROUND

Bronchial asthma is the most frequent chronic respiratory disease in both adults and children. The prevalence and burden of asthma vary considerably between different regions of the world. Information on asthma in Africa is fragmentary and relatively old.

OBJECTIVE

The objective of this cross-sectional epidemiological survey was to determine the prevalence and burden of asthma in the North African countries of Algeria, Morocco and Tunisia using the methodology developed in the Asthma Insights and Reality (AIR) programme.

METHODS

A general population sample was generated using a stratified sampling method based on randomly-generated lists of telephone numbers. The target sample consisted of 10,000 households in each country, which were contacted by telephone. A structured interview was proposed. Two screening questions were asked to identify subjects with asthma. Subjects who met these criteria were then questioned in more detail about their asthma.

RESULTS

Of 30 350 households contacted, 1090 subjects with asthma were identified of whom 872 provided complete data. The age- and gender-adjusted prevalence of asthma was 3.45% [95% CI: 3.09 3.80%] in Algeria, 3.89% [95% CI: 3.52 4.27%] in Morocco and 3.53% [95% CI: 3.18 3.89%] in Tunisia. Prevalence was highest in children and older adults, and in urban areas. Annual incidence rates ranged between 28/10,000 in Tunisia and 46/10,000 in Algeria. 74.3% of adults reported being handicapped by their asthma all or most of the time, 26.4% reported a visit to a hospital emergency department in the previous year and 23.9% absence from work or school due to asthma. 48.0% reported that their sleep was very or quite disturbed by asthma.

CONCLUSIONS

The prevalence of asthma in the Maghreb countries is moderate, but its impact is high.

摘要

背景

支气管哮喘是成人和儿童中最常见的慢性呼吸道疾病。哮喘的患病率和负担在世界不同地区差异很大。有关非洲哮喘的信息零散且相对陈旧。

目的

本横断面流行病学调查的目的是使用在哮喘洞察与现实(AIR)项目中开发的方法,确定北非国家阿尔及利亚、摩洛哥和突尼斯的哮喘患病率和负担。

方法

使用基于随机生成电话号码列表的分层抽样方法生成总体人群样本。目标样本由每个国家的 10000 户家庭组成,通过电话联系。提出了一项结构化访谈。提出了两个筛选问题来识别哮喘患者。符合这些标准的患者随后被更详细地询问他们的哮喘情况。

结果

在联系的 30350 户家庭中,确定了 1090 名哮喘患者,其中 872 名提供了完整数据。调整年龄和性别后的哮喘患病率为阿尔及利亚 3.45%[95%CI:3.09-3.80%]、摩洛哥 3.89%[95%CI:3.52-4.27%]和突尼斯 3.53%[95%CI:3.18-3.89%]。患病率在儿童和老年人以及城市地区最高。年发病率范围在突尼斯的 28/10000 至阿尔及利亚的 46/10000 之间。74.3%的成年人报告哮喘在所有或大部分时间都使他们残疾,26.4%报告在过去一年中去过医院急诊室,23.9%因哮喘缺勤或缺课。48.0%的人报告说哮喘非常或相当程度地干扰了他们的睡眠。

结论

马格里布国家的哮喘患病率适中,但影响很大。

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