Schwarzwälder Uwe, Zeller Thomas
Department Angiology, Heart Centre Bad Krozingen, Bad Krozingen, Germany.
Tech Vasc Interv Radiol. 2010 Mar;13(1):43-53. doi: 10.1053/j.tvir.2009.10.006.
During the past decade, the endovascular treatment of peripheral arterial disease has become more widespread due to the impressive extension of the endovascular toolbox to include different atherectomy technologies. The promise of atherectomy is to avoid the "barotraumas" defined as complications of traditional angioplasty such as dissection, elastic recoil, and disruption of the internal elastic lamina resulting in overwhelming neointima and smooth muscle cell proliferation. The oldest atherectomy technologies are the excimer laser and the Rotablator. The excimer laser technology is based on the principle of photoablation converting occlusive material into microbubbles being immediately dissolved into the blood. The Rotablator and the newer diamondback device are high speed rotational "sanding" devices particularly developed for the treatment of highly calcified plaque particularly in small vessel lesions, such as the popliteal and infrapopliteal segments. The Silverhawk system, currently the most widespread used device, is a directional atherectomy device particularly designed for eccentric and not severely calcified infrainguinal lesions whereas a variation of this device, the Rockhawk, is dedicated for the treatment of calcified plaques. The Jetstream system is the latest approved rotational atherectomy device focusing on native arteries with a reference vessel diameter of 4-6 mm in its current version; uniquely this device also has an aspiration capability making the device not only an atherectomy device but potentially also a thrombectomy device. This article will review the different indications for the use of these atherectomy devices including tips and specific device limitations.
在过去十年中,由于血管内治疗工具库显著扩展,纳入了不同的斑块旋切技术,外周动脉疾病的血管内治疗变得更加普遍。斑块旋切术的前景是避免传统血管成形术并发症所定义的“气压伤”,如夹层、弹性回缩以及内弹力层破坏,从而导致过度的新生内膜和平滑肌细胞增殖。最古老的斑块旋切技术是准分子激光和Rotablator。准分子激光技术基于光消融原理,将闭塞物质转化为微气泡,这些微气泡会立即溶解于血液中。Rotablator和更新的Diamondback装置是高速旋转的“打磨”装置,专门用于治疗高度钙化的斑块,特别是在小血管病变中,如腘动脉和腘以下动脉节段。Silverhawk系统是目前使用最广泛的装置,是一种定向斑块旋切装置,特别设计用于治疗偏心且钙化不严重的腹股沟下病变,而该装置的一种变体Rockhawk则专门用于治疗钙化斑块。Jetstream系统是最新获批的旋转斑块旋切装置,其当前版本主要针对参考血管直径为4 - 6毫米的天然动脉;独特的是,该装置还具有抽吸功能,这使得该装置不仅是一种斑块旋切装置,还可能是一种血栓清除装置。本文将综述这些斑块旋切装置的不同使用指征,包括技巧和特定装置的局限性。