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除非另有证明,否则角膜溃疡的病因假定为猫疱疹病毒1型。

Aetiology of corneal ulcers assume FHV-1 unless proven otherwise.

作者信息

Hartley Claudia

机构信息

Animal Health Trust, Lanwades Park, Kentford, Newmarket, Suffolk CB8 7UU, UK.

出版信息

J Feline Med Surg. 2010 Jan;12(1):24-35. doi: 10.1016/j.jfms.2009.12.004.

Abstract

OVERVIEW

Feline ulcerative keratitis is a common presenting complaint and is frequently a sequela of feline herpesvirus 1 (FHV-1) infection; so much so, in fact, that it is fair to assume an FHV-1 aetiology until proven otherwise. Other potential causes of ulceration are trauma or underlying eyelid abnormalities (entropion, ectropion, agenesis, dermoids, neoplasia), lash abnormalities (ectopic cilia, trichiasis), tear film abnormalities or neurological deficiencies (trigeminal nerve paralysis, facial nerve paralysis).

CLINICAL CHALLENGES

The management of corneal ulceration in cats is frequently challenging, and treatment needs to be tailored carefully to the individual cat, its temperament, and the disease process present.

EVIDENCE BASE

The scientific literature on feline ulcerative keratitis is extensive, particularly that related to FHV-1 infection. The aim of this article is to review the aetiology and diagnosis of corneal ulceration in cats with particular reference to the evidence base available.

PATIENT GROUP

All age groups and breeds can suffer with ulcerative keratitis. Breed predispositions are present for some forms of corneal ulceration, and these are discussed.

摘要

概述

猫溃疡性角膜炎是常见的就诊主诉,常为猫疱疹病毒1型(FHV-1)感染的后遗症;事实上,在未证明有其他病因之前,假定其病因是FHV-1感染是合理的。溃疡形成的其他潜在原因包括外伤或潜在的眼睑异常(睑内翻、睑外翻、发育不全、皮样囊肿、肿瘤)、睫毛异常(异位睫、倒睫)、泪膜异常或神经功能缺陷(三叉神经麻痹、面神经麻痹)。

临床挑战

猫角膜溃疡的治疗通常具有挑战性,需要根据每只猫的个体情况、性情以及当前的疾病进程进行精心调整。

证据基础

关于猫溃疡性角膜炎的科学文献很多,尤其是与FHV-1感染相关的文献。本文旨在回顾猫角膜溃疡的病因和诊断,并特别参考现有的证据基础。

患者群体

所有年龄组和品种的猫都可能患溃疡性角膜炎。某些形式的角膜溃疡存在品种易感性,本文将对此进行讨论。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a31/10845471/c626847d2042/10.1016_j.jfms.2009.12.004-fig19.jpg

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