Droupy S, Giuliano F, Costa P
Service d'Urologie-Andrologie, CHU de Nîmes, Place du Professeur Robert Debré, 30000 Nîmes, Université Montpellier 1, France.
Prog Urol. 2009 Dec;19 Suppl 4:S193-7. doi: 10.1016/S1166-7087(09)73373-1.
The concept of penile rehabilitation involves the procedures designed to improve oxygen delivery the penile erectile tissue to minimized tissue damage during the period of neural recovery following radical prostatectomy. Many basic research studies support the rationale and mechanism of the concept of penile rehabilitation, however they are few clinical studies in the literature that provide a clear medical evidence of its efficacy in patients. Waiting for new data, it is recommended to propose to the patients, following a radical prostatectomy, an active pharmacological penile rehabilitation. This rehabilitation involves counselling with the couple to have regular sexual activities, ideally 1 to 3 times a week. Penile erections could be induced by intracavernosal injections of PGE1 or improved by using PDE5 inhibitors on demand. The results of daily use of PDE5 inhibitor are conflicting and then it cannot be recommended systematically waiting for new data. The rehabilitation could be maintained for about 2 years as results improve with time.
阴茎康复的概念涉及旨在改善阴茎勃起组织的氧气供应，以在根治性前列腺切除术后的神经恢复期间将组织损伤降至最低的程序。许多基础研究支持阴茎康复概念的基本原理和机制，然而，文献中很少有临床研究能为其对患者的疗效提供明确的医学证据。在等待新数据期间，建议在根治性前列腺切除术后向患者提议进行积极的药物阴茎康复治疗。这种康复包括与夫妻双方进行咨询，以进行规律的性活动，理想情况下每周1至3次。阴茎勃起可通过海绵体内注射前列地尔诱导，或按需使用磷酸二酯酶5抑制剂改善。每日使用磷酸二酯酶5抑制剂的结果存在矛盾，因此在等待新数据期间不能系统地推荐使用。随着时间推移结果会改善，康复治疗可维持约2年。
