Mulhall John P, Morgentaler Abraham
Sexual Medicine Program, Department of Urology, Memorial Sloan Kettering Cancer Center, New York, NY, USA;.
Men's Health Boston, Department of Urology, Harvard Medical School, Boston, MA, USA.
J Sex Med. 2007 May;4(3):538-543. doi: 10.1111/j.1743-6109.2007.00486.x.
The Journal of Sexual Medicine (JSM) held a debate at the annual fall meeting of the Sexual Medicine Society of North America (SMSNA). The motion was "Penile Rehabilitation Should Become the Norm for Radical Prostatectomy Patients." At the suggestion of several SMSNA members, it was requested that this debate might be of interest to JSM readers in the form of a published controversy.
Two debate speakers with expertise and/or strong opinions in the area of penile rehabilitation submitted their literature-review, evidence-based opinions on the topic.
Literature review of laboratory basic science and clinical research studies on penile rehabilitation.
Penile rehabilitation involves prophylactic procedures designed to improve oxygen delivery to penile erectile tissues, aimed at preserving erectile tissue health and minimizing erectile tissue damage that otherwise occurs during the period of neural recovery to the autonomic cavernosal nerve following radical prostatectomy. There are several studies in the sexual medicine literature on penile rehabilitation after radical prostatectomy, and the positive results appear to support this concept, the rationale, and mechanism. The use of prophylactic penile rehabilitation programs has not been fully elucidated, nor have the results been replicated in large multicenter placebo-controlled trials.
Penile rehabilitation may be performed along with counseling with the couple, vacuum erection therapy, and vacuum erection device therapy if it is the patient and partner's preference, provided that it is undertaken in a safe and effective manner and is monitored closely.
《性医学杂志》(JSM)在北美性医学学会(SMSNA)年度秋季会议上举办了一场辩论。辩题是“阴茎康复应成为根治性前列腺切除术患者的常规治疗手段”。应几位SMSNA成员的建议,决定以发表争议文章的形式将这场辩论呈现给JSM的读者,他们可能会对此感兴趣。
两位在阴茎康复领域有专业知识和/或强烈观点的辩论发言者提交了他们基于文献综述和证据的关于该主题的观点。
对阴茎康复的实验室基础科学和临床研究进行文献综述。
阴茎康复包括预防性措施,旨在改善阴茎勃起组织的氧气供应,目的是保持勃起组织健康,并将根治性前列腺切除术后自主海绵体神经神经恢复期间原本会发生的勃起组织损伤降至最低。性医学文献中有多项关于根治性前列腺切除术后阴茎康复的研究,其积极结果似乎支持这一概念、基本原理和机制。预防性阴茎康复方案的应用尚未完全阐明,其结果也未在大型多中心安慰剂对照试验中得到重复验证。
如果患者及其伴侣有此意愿,阴茎康复可与对伴侣的咨询、真空勃起疗法和真空勃起装置疗法同时进行,前提是要以安全有效的方式进行并密切监测。