Gassara M, Delongchamps N Barry, Legrand G, Vieillefond A, Saighi D, Debré B, Conquy S, Zerbib M
Service d'urologie, hôpital Cochin, université Paris-Descartes, Paris, France.
Prog Urol. 2010 Jan;20(1):80-2. doi: 10.1016/j.purol.2009.02.010. Epub 2009 Apr 5.
Primary urethral melanoma is a rare pathology for which treatment strategies are controversial. The aim of this work was to report a case of metastatic primary urethral melanoma, and to discuss recent data available from literature.
Case study was summarized from the patient's medical chart. Review of literature was performed using the National Center for Biotechnology Information (NCBI) database.
We reported the case of an 89-year-old woman who died from a primary metastatic melanoma of the urethra. This pathology encounters for less than 1% of melanomas and has an adverse prognosis. In case of metastasis, specific survival is only of a few months. When localized to the urethra, treatment relies on radical urethrectomy, followed by adjuvant chemo- and immunotherapy.
The modalities of treatment of primary urethral melanoma rely only on reported case studies. When diagnosed at the metastatic stage, reported specific survival does not exceed a few months.
