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兔模型中锈环去除方法的比较:小口径皮下注射针与电钻

A comparison of rust-ring removal methods in a rabbit model: small-gauge hypodermic needle versus electric drill.

作者信息

Liston R L, Olson R J, Mamalis N

机构信息

Department of Ophthalmology, University of Utah School of Medicine, Salt Lake City.

出版信息

Ann Ophthalmol. 1991 Jan;23(1):24-7.

PMID:2012370
Abstract

Corneal rust rings are common findings after removal of a metallic foreign body. These rings should be removed to prevent inflammation and scarring. We compared the corneal damage in rabbit eyes caused by rust-ring removal using two different methods: a small-gauge hypodermic needle and a hand-held electric ophthalmic drill. No significant difference was found in the amount of corneal scarring as graded by a masked observer. However, there was a trend toward deeper stromal damage in the drill-treated subjects (207 +/- 73 microns) than in the needle-treated subjects (172 +/- 61 microns). In light of this finding, we suggest caution in removing central rust rings with an electric drill since an avoidable, permanent scar may result.

摘要

角膜锈环是取出金属异物后的常见表现。应去除这些锈环以预防炎症和瘢痕形成。我们使用两种不同方法比较了去除兔眼角膜锈环所造成的角膜损伤:小口径皮下注射针和手持式电动眼科钻。由一位不知情的观察者分级评估,发现角膜瘢痕量无显著差异。然而,使用钻治疗的受试者角膜基质损伤深度(207±73微米)比使用针治疗的受试者(172±61微米)有加深的趋势。鉴于这一发现,我们建议谨慎使用电动钻去除中央锈环,因为可能会导致不可避免的永久性瘢痕。

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