Suppr超能文献

八旬老人的开胸手术

Thoracotomy in the octogenarian.

作者信息

Naunheim K S, Kesler K A, D'Orazio S A, Fiore A C, McBride L R, Judd D R

机构信息

Department of Surgery, St. Louis University Medical Center, Missouri 63110-0250.

出版信息

Ann Thorac Surg. 1991 Apr;51(4):547-50; discussion 550-1. doi: 10.1016/0003-4975(91)90308-d.

Abstract

Octogenarians are rarely referred for thoracic operations, presumably owing to the perceived morbidity of thoracotomy and the presumed frailty and limited life span of the 80-year-old patient. To determine if these concerns are valid, we reviewed our operative experience in 50 patients 80 years of age or older (mean age, 82.7 years; range, 80 to 91 years; 29 men, 21 women) undergoing thoracotomy between Nov 1, 1980, and May 1, 1990, for cancer (39 patients) and benign disease (11 patients). Procedures included 25 lobectomies (24 cancer, 1 abscess), 4 pneumonectomies (all cancer), 3 esophagectomies (1 perforation, 2 cancer), 3 explorations for cancer, 2 bullectomies, 12 wedge or segmental resections (5 open lung biopsies, 5 cancer, and 1 each for benign nodule and hemoptysis), and 1 thymectomy. Five patients (10%) were operated on emergently for massive hemoptysis (1), Boerhaave's syndrome (1), or rapidly progressive respiratory insufficiency (3) with an operative mortality of 80%. Mortality for elective cases was significantly lower (13%, p less than 0.01). Major complications occurred in 19 patients (38%). Univariate analysis performed to identify predictors of operative mortality demonstrated no significant relationship between operative death and patient age, sex, type of operation, diagnosis of malignancy, or the presence of either cardiac disease or chronic obstructive lung disease. Twenty-three patients are alive 2 months to 5 years after thoracotomy. Actuarial survival for the 45 elective patients was 56% and 44% at 1 and 2 years, respectively.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

八旬老人很少接受胸外科手术,推测原因是开胸手术的发病率以及人们认为80岁患者身体虚弱且寿命有限。为了确定这些担忧是否合理,我们回顾了1980年11月1日至1990年5月1日期间50例80岁及以上(平均年龄82.7岁;范围80至91岁;29例男性,21例女性)接受开胸手术患者的手术经验,这些患者因癌症(39例)和良性疾病(11例)接受手术。手术包括25例肺叶切除术(24例癌症,1例脓肿)、4例全肺切除术(均为癌症)、3例食管切除术(1例穿孔,2例癌症)、3例癌症探查术、2例肺大疱切除术、12例楔形或节段性切除术(5例开胸肺活检,5例癌症,1例良性结节和1例咯血各1例)以及1例胸腺切除术。5例患者(10%)因大量咯血(1例)、Boerhaave综合征(1例)或快速进展性呼吸功能不全(3例)接受急诊手术,手术死亡率为80%。择期手术患者的死亡率显著较低(13%,p<0.01)。19例患者(38%)发生了主要并发症。进行单因素分析以确定手术死亡率的预测因素,结果显示手术死亡与患者年龄、性别、手术类型、恶性肿瘤诊断或是否存在心脏病或慢性阻塞性肺疾病之间无显著关系。23例患者在开胸手术后2个月至5年存活。45例择期手术患者的1年和2年精算生存率分别为56%和44%。(摘要截断于250字)

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验